1,1-双(三甲基甲硅烷氧基)-1-丙烯合成路线 （共 10 条）
反应条件
1: Propansaeure-trimethylsilylester With n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78 - 20°C; 12 h;
参考文献
Rotzoll, Sven; Ullah, Ehsan; Goerls, Helmar; Fischer, Christine; Langer, Peter
Tetrahedron, 2007 , vol. 63, # 12 p. 2647 - 2656
反应条件
(i) LDA, (ii) /BRN= 1209232/; Multistep reaction;
参考文献
Ullah, Ehsan; Langer, Peter
Synlett, 2004 , # 15 p. 2782 - 2784
反应条件
triethylamine in diethyl ether 4 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Emde, Herbert; Simchen, Gerhard
Liebigs Annalen der Chemie, 1983 , # 5 p. 816 - 834
反应条件
acetic acid; lithium diisopropyl amide 1) THF, -78 deg C -> 50 deg C, 24 h; 2) -78 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bellassoued, M.; Dubois, J. E.; Bertounesque, E.
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 4 p. 263 - 266
反应条件
Yield givenMultistep reaction;
参考文献
Bellassoued, Moncef; Chelain, Evelyne; Collot, Jerome; Rudler, Henri; Vaissermann, Jacqueline
Chemical Communications, 1999 , # 2 p. 187 - 188
反应条件
zinc(II) chloride in dichloromethane Ambient temperature;
参考文献
Reetz, Manfred T.; Schwellnus, Konrad; Huebner, Friedhelm; Massa, Werner; Schmidt, Roland E.
Chemische Berichte, 1983 , vol. 116, # 11 p. 3708 - 3724
反应条件
1: 4-phenyl-3-butyn-2-one With boron trifluoride diethyl etherate in diethyl ether
T=0°C; 0.05 h; Inert atmosphere;
2: 4-ethylidene-2,2,6,6-tetramethyl-3,5-dioxa-2,6-disilaheptane in diethyl ether
T=0 - 20°C; 4 h; Inert atmosphere; Overall yield = 94 percent;
参考文献
Lopez-Reyes, Morelia E.; Lopez-Cortes, Jose G.; Ortega-Alfaro, M. Carmen; Toscano, R. Alfredo; Alvarez-Toledano, Cecilio
Tetrahedron, 2013 , vol. 69, # 35 p. 7365 - 7372
反应条件
SO3*dioxane
Yield given;
参考文献
Sergeev, V. N.; Baukov, Yu. I.
J. Gen. Chem. USSR (Engl. Transl.), 1983 , vol. 53, # 3 p. 710 - 711,619 - 620
反应条件
zinc(II) chloride
T=0°C; 1 h;
参考文献
Reetz, Manfred T.; Walz, Peter; Huebner, Friedhelm; Huettenhain, Stefan H.; Heimbach, Horst; Schwellnus, Konrad
Chemische Berichte, 1984 , vol. 117, # 1 p. 322 - 335
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane
T=25 - 30°C; 1 h;
参考文献
Okano, Kohji; Morimoto, Toshiaki; Sekiya, Minoru
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 6 p. 2228 - 2234
