2-氯-四氢-2H-吡喃合成路线 （共 20 条）
反应条件
ethylmagnesium bromide
1.) THF, 25 - 30 deg C, 6.5 h, 2.) (C2H5)2O, THF, room temp., overnight; Yield given. Multistep reaction;
参考文献
Viola, Alfred; Collins, John J.; Filipp, Nicholas; Locke, John S.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5067 - 5075
反应条件
1: 1.) C2H5MgBr / 1.) THF, 25 - 30 deg C, 6.5 h, 2.) (C2H5)2O, THF, room temp., overnight
2: 35 percent Chromat. / 420 °C / 63 Torr
View Scheme
参考文献
Viola, Alfred; Collins, John J.; Filipp, Nicholas; Locke, John S.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5067 - 5075
反应条件
in N,N-dimethyl-formamide
参考文献
Fife, Thomas H.; Przystas, Theodore J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987 , p. 143 - 150
反应条件
tin(IV) chloride in dichloromethane
4 h; Ambient temperature;
参考文献
Reetz, Manfred T.; Chatziiosifidis, Ioannis; Kuenzer, Hermann; Mueller-Starke, Hans
Tetrahedron, 1983 , vol. 39, # 6 p. 961 - 966
反应条件
in diethyl ether
3 h; Heating;
参考文献
Booth, Harold; Dixon, J. Mark; Khedhair, Khedhair A.
Tetrahedron, 1992 , vol. 48, # 29 p. 6161 - 6174
反应条件
trimethylsilyl iodide in dichloromethane
T=-78°C; 0.0833333 h;
参考文献
Hosomi, Akira; Sakata, Yasuyuki; Sakurai, Hideki
Chemistry Letters, 1983 , p. 405 - 408
反应条件
trimethylsilyl iodide in dichloromethane
T=-78°C; 0.0833333 h;
参考文献
Hosomi, Akira; Sakata, Yasuyuki; Sakurai, Hideki
Chemistry Letters, 1983 , p. 405 - 408
反应条件
trimethylsilyl iodide in dichloromethane
T=-78°C; 0.0833333 h;
参考文献
Hosomi, Akira; Sakata, Yasuyuki; Sakurai, Hideki
Chemistry Letters, 1983 , p. 405 - 408
反应条件
trimethylsilyl iodide in dichloromethane
T=-78 - -20°C; 0.333333 h;
参考文献
Sakurai, Hideki; Sakata, Yasuyuki; Hosomi, Akira
Chemistry Letters, 1983 , p. 409 - 412
反应条件
trimethylsilyl iodide in dichloromethane
T=-78°C; 0.0833333 h;
参考文献
Hosomi, Akira; Sakata, Yasuyuki; Sakurai, Hideki
Chemistry Letters, 1983 , p. 405 - 408
