1-溴-2-甲基-1-丙烯合成路线 (共 93 条)
反应条件
Zinc chloride in tetrahydrofuran; ethyl acetate
参考文献
Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: US2004/10148 A1, 2004 ;
US 20040010148 A1
参考文献
Butlerow
Zeitschrift fuer Chemie, 1870 , p. 524
反应条件
tri-n-butyltin methoxide; bis (triortho-tolylphosphine)palladium(II) chloride in toluene
T=100°C; 0.5 h;
参考文献
Kosugi, Masanori; Hagiwara, Isao; Migita, Toshihiko
Chemistry Letters, 1983 , p. 839 - 840
反应条件
copper(l) iodide; N-butylamine; tetrakis(triphenylphosphine) palladium(0) in benzene
T=20°C; Sonogashira coupling;
参考文献
Burke, Christopher P.; Shi, Yian
Journal of Organic Chemistry, 2007 , vol. 72, # 11 p. 4093 - 4097
参考文献
Wilt
Journal of the American Chemical Society, 1955 , vol. 77, p. 6397
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Gramenizkaja et al.
Doklady Akademii Nauk SSSR, 1958 , vol. 118, p. 497,498
Doklady Chemistry, 118-123 <1958> 65, 66
反应条件
methanol; copper(I) bromide
T=80°C; 4 h;
参考文献
Keegstra
Tetrahedron, 1992 , vol. 48, # 13 p. 2681 - 2690
反应条件
magnesium
Yield given. Multistep reaction;
参考文献
Barbot, Francis; Poncini, Laurence; Randrianoelina, Benjamin; Miginiac, Philippe
Journal of Chemical Research, Miniprint, 1981 , # 11 p. 4016 - 4035
反应条件
methanol; copper(I) bromide
T=80°C; 4 h;
参考文献
Keegstra
Tetrahedron, 1992 , vol. 48, # 13 p. 2681 - 2690
参考文献
Eltekow
Chemische Berichte, 1877 , vol. 10, p. 705
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1877 , vol. 9, p. 163
参考文献
Soderquist, John A.; Lee, Shwn-Ji Hwang
Tetrahedron, 1988 , vol. 44, # 13 p. 4033 - 4042