5-溴烟酸甲酯合成路线

参考文献

Thompson, Wayne J.; Jones, James H.; Lyle, Paulette A.; Thies, J. Eric
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2052 - 2055

29681-44-55-溴烟酸甲酯

124236-38-05-(三氟甲基)烟酸甲酯

参考文献

Mormino, Michael G.; Fier, Patrick S.; Hartwig, John F.
Organic Letters, 2014 , vol. 16, # 6 p. 1744 - 1747

29681-44-55-溴烟酸甲酯+

1692-15-5吡啶-4-硼酸

113893-01-9

参考文献

Thompson, Wayne J.; Jones, James H.; Lyle, Paulette A.; Thies, J. Eric
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2052 - 2055

29681-44-55-溴烟酸甲酯

885274-99-75-苯基哌啶-1,3-二羧酸-1-叔丁酯

参考文献

DeNinno, Michael P.; Wright, Stephen W.; Visser, Michael S.; Etienne, John B.; Moore, Dianna E.; Olson, Thanh V.; Rocke, Benjamin N.; Andrews, Melissa P.; Zarbo, Cynthia; Millham, Michele L.; Boscoe, Brian P.; Boyer, David D.; Doran, Shawn D.; Houseknecht, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3095 - 3098

872-50-4N-甲基吡咯烷酮+

29681-44-55-溴烟酸甲酯

88909-26-6

参考文献

Gandhi, Paresh T.
Patent: US2013/123106 A1, 2013 ;
Location in patent: Paragraph 0091; 0092 ;

29681-44-55-溴烟酸甲酯+

635305-47-43-氯苯基硼酸片呐醇酯

893734-67-3

参考文献

Bossenmaier, Birgit; Friess, Thomas; Juchem, Rolf; Kling, Lothar; Kolm, Irene; Krell, Hans-Willi; von Hirschheydt, Thomas; Voss, Edgar
Patent: US2007/32530 A1, 2007 ;
Location in patent: Page/Page column 27 ;

29681-44-55-溴烟酸甲酯+

1679-18-14-氯苯硼酸

893734-71-9

参考文献

Bossenmaier, Birgit; Friess, Thomas; Juchem, Rolf; Kling, Lothar; Kolm, Irene; Krell, Hans-Willi; von Hirschheydt, Thomas; Voss, Edgar
Patent: US2007/32530 A1, 2007 ;
Location in patent: Page/Page column 25-26 ;

29681-44-55-溴烟酸甲酯+

128796-39-44-三氟甲基苯硼酸

893734-81-1

参考文献

BAYER PHARMA AKTIENGESELLSCHAFT
Patent: US2012/149694 A1, 2012 ;
Location in patent: Page/Page column 18; 21 ;

29681-44-55-溴烟酸甲酯+

1423-26-33-(三氟甲基)苯硼酸

893734-85-5

参考文献

BANYU PHARMACEUTICAL CO., LTD.; VERTEX PHARMACEUTICALS INCORPORATED; BINCH, Hayley; HASHIMOTO, Masaya; MORTIMORE, Michael; OHKUBO, Mitsuru; SUNAMI, Tomoko
Patent: WO2010/111056 A1, 2010 ;
Location in patent: Page/Page column 38-39 ;
WO 2010/111056 A1

29681-44-55-溴烟酸甲酯+

921760-66-9

921760-67-06-(5-(甲氧基羰基)吡啶-3-基)-4-氧代螺[苯并二氢吡喃-2,4-哌啶]-1-羧酸叔丁酯

参考文献

MERCK and CO., INC.; BANYU PHARMACEUTICAL CO., LTD.
Patent: WO2008/88692 A2, 2008 ;
Location in patent: Page/Page column 17 ;