5-溴烟酸甲酯合成路线

参考文献

Hamel, Pierre; Riendeau, Denis; Brideau, Christine; Chan, Chi-Chung; Desmarais, Sylvie; Delorme, Daniel; Dube, Daniel; Ducharme, Yves; Ethier, Diane; Grimm, Erich; Falgueyret, Jean-Pierre; Guay, Jocelyne; Jones, Tom R.; Kwong, Elizabeth; McAuliffe, Malia; McFarlane, Cyril S.; Piechuta, Hanna; Roumi, Marie; Tagari, Philip; Young, Robert N.; Girard, Yves
Journal of Medicinal Chemistry, 1997 , vol. 40, # 18 p. 2866 - 2875

29681-44-55-溴烟酸甲酯+

544-92-3氰化亚铜

106726-82-35-氰基-3-吡啶甲酸甲酯

参考文献

ELI LILLY AND COMPANY
Patent: WO2005/66126 A1, 2005 ;
Location in patent: Page/Page column 66 ;
WO 2005/066126 A1

29681-44-55-溴烟酸甲酯

112193-41-65-溴吡啶-3-甲酰肼

参考文献

BRISTOL-MYERS SQUIBB COMPANY; JOHNSON, James A.; LLOYD, John; FINLAY, Heather; JIANG, Ji; NEELS, James; DHONDI, Naveen Kumar; GUNAGA, Prashantha; BANERJEE, Abhisek; ADISECHAN, Ashokkumar
Patent: WO2011/28741 A1, 2011 ;
Location in patent: Page/Page column 346 ;
WO 2011/028741 A1

29681-44-55-溴烟酸甲酯

1095010-47-11-Boc-5-羟基-3-哌啶甲酸甲酯

参考文献

DeNinno, Michael P.; Wright, Stephen W.; Visser, Michael S.; Etienne, John B.; Moore, Dianna E.; Olson, Thanh V.; Rocke, Benjamin N.; Andrews, Melissa P.; Zarbo, Cynthia; Millham, Michele L.; Boscoe, Brian P.; Boyer, David D.; Doran, Shawn D.; Houseknecht, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3095 - 3098

29681-44-55-溴烟酸甲酯+

73183-34-3联硼酸频那醇酯

1025718-91-53-(甲氧羰基)吡啶-5-硼酸频那醇酯

参考文献

XCOVERY, INC.
Patent: WO2008/88881 A1, 2008 ;
Location in patent: Page/Page column 49 ;
WO 2008/088881 A1

29681-44-55-溴烟酸甲酯+

40473-07-22-溴-6-甲氧基吡啶

128612-43-1二甲基-3,3’-联砒啶-5,5’-二羧酸+

321535-19-7

参考文献

O'Neill, Brian T.; Yohannes, Daniel; Bundesmann, Mark W.; Arnold, Eric P.
Organic Letters, 2000 , vol. 2, # 26 p. 4201 - 4204

29681-44-55-溴烟酸甲酯

128612-43-1二甲基-3,3’-联砒啶-5,5’-二羧酸

参考文献

Iyoda; Otsuka; Sato; Nisato; Oda
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 1 p. 80 - 87

29681-44-55-溴烟酸甲酯

1095010-44-85-羟基-3-哌啶甲酸甲酯

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 3095 - 3098

29681-44-55-溴烟酸甲酯

1095010-48-21-Boc-5-羟基-3-哌啶甲酸

参考文献

DeNinno, Michael P.; Wright, Stephen W.; Visser, Michael S.; Etienne, John B.; Moore, Dianna E.; Olson, Thanh V.; Rocke, Benjamin N.; Andrews, Melissa P.; Zarbo, Cynthia; Millham, Michele L.; Boscoe, Brian P.; Boyer, David D.; Doran, Shawn D.; Houseknecht, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3095 - 3098

29681-44-55-溴烟酸甲酯

29681-45-65-甲基烟酸甲酯

参考文献

DeNinno, Michael P.; Wright, Stephen W.; Visser, Michael S.; Etienne, John B.; Moore, Dianna E.; Olson, Thanh V.; Rocke, Benjamin N.; Andrews, Melissa P.; Zarbo, Cynthia; Millham, Michele L.; Boscoe, Brian P.; Boyer, David D.; Doran, Shawn D.; Houseknecht, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3095 - 3098