2,5-二溴己烷二基二氯化物合成路线 （共 9 条）
反应条件
1: 1,6-hexanedioic acid With thionyl chloride T=80°C; 2: bromine With thionyl chloride T=80°C;
参考文献
Yang, Ke-Wu; Feng, Lei; Yang, Shao-Kang; Aitha, Mahesh; Lacuran, Alecander E.; Oelschlaeger, Peter; Crowder, Michael W.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 21 p. 5855 - 5859
反应条件
bromine T=75 - 85°C; 2 h; Irradiation;
参考文献
Uneme, Hideki; Mitsudera, Hiroyuki; Kamikado, Toshiya; Kono, Yoshiaki; Manabe, Yukiaki; Numata, Mitsuo
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 12 p. 2023 - 2033
反应条件
1: SOCl2 / 3 h / 50 - 60 °C 2: Br2 / 7 h / 80 - 90 °C View Scheme
参考文献
Mhenni, F.; Bouraoui, A.; Mighri, Z.; Gallo, R.
Bulletin de la Societe Chimique de France, 1989 , # 6 p. 824 - 829
参考文献
Liu, Hong; Cheng, Tie-Ming; Zhang, Hong-Mei; Li, Run-Tao
Archiv der Pharmazie, 2003 , vol. 336, # 11 p. 510 - 513
反应条件
1: 71 percent / methanol / 56 h / 75 °C View Scheme
参考文献
Daly, Adrian M.; Gilheany, Declan G.
Tetrahedron Asymmetry, 2003 , vol. 14, # 1 p. 127 - 137
反应条件
2) MeOH; Multistep reaction;
参考文献
Earl, Harald A.; Marshall, Donald R.; Stirling, Charles J. M.
Journal of the Chemical Society, Chemical Communications, 1983 , # 13 p. 779 - 781
反应条件
1: 71 percent / methanol / 56 h / 75 °C 2: aq. HCl / 12 h / Heating View Scheme
参考文献
Daly, Adrian M.; Gilheany, Declan G.
Tetrahedron Asymmetry, 2003 , vol. 14, # 1 p. 127 - 137
反应条件
1: 71 percent / methanol / 56 h / 75 °C 2: aq. HCl / 12 h / Heating 3: 180 °C / water pump View Scheme
参考文献
Daly, Adrian M.; Gilheany, Declan G.
Tetrahedron Asymmetry, 2003 , vol. 14, # 1 p. 127 - 137
反应条件
1: 71 percent / methanol / 56 h / 75 °C
2: aq. HCl / 12 h / Heating
3: 180 °C / water pump
4: 96 percent / SOCl2 / benzene / 24 h / 70 °C
View Scheme
参考文献
Daly, Adrian M.; Gilheany, Declan G.
Tetrahedron Asymmetry, 2003 , vol. 14, # 1 p. 127 - 137
