3-(三甲硅基)-1-丙醇合成路线 (共 32 条)
反应条件
hydrogenchloride in not given (CH3)3SiCH2MgCl and ethylene oxide; hydrolysis with HCl;;
参考文献
Sommer; Van Strien; Whitmore
Journal of the American Chemical Society, 1949 , vol. 71, p. 3056
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Speier, J. L.
Journal of the American Chemical Society, 1952 , vol. 74, p. 1003 - 1010
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Gmelin Handbook: Si: MVol.C, 9, page 28 - 32
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Dow Corning Corp.
Patent: US2557802 , 1951 ;
C. A., 1952 , p. 1026
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Dow Corning Corp.
Patent: US2629727 , 1953 ;
C. A., 1954 , p. 1418
反应条件
lithium in pentane 4 h; Heating;
参考文献
Maercker, Adalbert; Eckers, Mechthild; Passlack, Michael
Journal of Organometallic Chemistry, 1980 , vol. 186, # 2 p. 193 - 205
反应条件
oxygen; aluminum dichloride hydride; triethyl borane 1) ether, RT, 2) RT, 3 h; Yield given. Multistep reaction;
参考文献
Diez-Gonzalez, Silvia; Paugam, Renee; Blanco, Luis
European Journal of Organic Chemistry, 2008 , # 19 p. 3298 - 3307
反应条件
hydrogenchloride 0.5 h; Heating; Yield given;
参考文献
Gmelin Handbook: Si: MVol.C, 80, page 222 - 225
反应条件
hydrogen; nickel in ethanol
参考文献
Komarov,N.V.; Shostakovskii,M.F.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1960 , p. 1208 - 1210
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1960 , # 7 p. 1300 - 1302
反应条件
lithium aluminium tetrahydride
参考文献
Fessenden; Coon
Journal of medicinal chemistry, 1965 , vol. 8, # 5 p. 604 - 608
反应条件
sodium; chloromethyl-trimethyl-silane in diethyl ether Heating;
参考文献
Vdovin,V.M. et al.
Doklady Chemistry, 1961 , vol. 138, # 4 p. 526 - 529
Doklady Akademii Nauk SSSR, 1961 , vol. 138, # 4 p. 831 - 834
参考文献
Sarkar, Tarun K.; Ghosh, Sunil K.
Tetrahedron Letters, 1987 , vol. 28, # 18 p. 2061 - 2064
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 25°C; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Denmark, S. E.; Jones, T. K.
Journal of Organic Chemistry, 1982 , vol. 47, # 23 p. 4595 - 4597
参考文献
Smirnova,G.S. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1971 , vol. 41, # 12 p. 2684 - 2688,2718 - 2721