3,4-二氯-3-环丁烯-1,2-二酮合成路线 （共 26 条）
反应条件
N,N-dimethyl-formamide in dichloromethane
1) 2 h, room temp.; 30 min, reflux;
参考文献
Schmidt, Arthur H.; Plaul, Wolfgang; Aimene, Amokrane; Hotz, Monika; Hoch, Monika
Liebigs Annalen der Chemie, 1985 , # 5 p. 1021 - 1035
反应条件
N,N-dimethyl-formamide in dichloromethane
1) 2 h, room temp.; 30 min, reflux;
参考文献
Schmidt, Arthur H.; Plaul, Wolfgang; Aimene, Amokrane; Hotz, Monika; Hoch, Monika
Liebigs Annalen der Chemie, 1985 , # 5 p. 1021 - 1035
反应条件
triethylamine in dichloromethane
T=0°C; 1 h;
参考文献
Sejwal, Preeti; Han, Yongbin; Shah, Akshay; Luk, Yan-Yeung
Organic Letters, 2007 , vol. 9, # 23 p. 4897 - 4900
反应条件
in dichloromethane
0.5 h; Heating;
参考文献
Schmidt, Arthur H.; Plaul, Wolfgang; Aimene, Amokrane; Hotz, Monika; Hoch, Monika
Liebigs Annalen der Chemie, 1985 , # 5 p. 1021 - 1035
反应条件
triethylamine in tetrahydrofuran
2 h; Ambient temperature;
参考文献
Zinner; Grunefeld
Archiv der Pharmazie, 1985 , vol. 318, # 11 p. 977 - 983
反应条件
n-butyllithium; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane
Ar atmosphere; stirring of Fe-compd. in THF (-70°C, 10 min), addn. of BuLi in hexane, stirring (10 min), cooling (ice bath), addn. ZnI2, stirring (10 min), addn. to soln. of org. compd. and Pd-compd., stirring (3 h, removal of cooling after 2 h); evapn. (vac.), addn. of Et2O, partial evapn., chromy.(silica, hexane/Et2O 70:30);
参考文献
Schottenberger, Herwig; Buchmeiser, Michael; Polin, Johann; Schwarzhans, Karl-Eberhard
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1993 , vol. 48, # 11 p. 1524 - 1532
