3,3-二甲基-1-氯丁烷合成路线 （共 54 条）
参考文献
Universal Oil Prod.Co.
Patent: US2404927 , 1943 ;
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Schmerling
Journal of the American Chemical Society, 1944 , vol. 66, p. 1423
反应条件
1.1: NaH; KI / dimethylformamide / 0 - 20 °C 1.2: dimethylformamide / 12 h / 80 °C 2.1: aq. KOH / ethanol / 12 h / Heating 3.1: 36 percent / 150 °C 4.1: LiAlH4 / diethyl ether / 12 h / Heating View Scheme
参考文献
Sasse, Astrid; Ligneau, Xavier; Rouleau, Agnes; Elz, Sigurd; Ganellin, C. Robin; Arrang, Jean-Michel; Schwartz, Jean-Charles; Schunack, Walter; Stark, Holger
Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 4000 - 4010
反应条件
(i) Mg, (ii) /BRN= 102378/; Multistep reaction;
参考文献
Desai,V.R. et al.
Journal of the Chemical Society [Section] B: Physical Organic, 1970 , p. 386 - 388
反应条件
1.1: NaH; KI / dimethylformamide / 0 - 20 °C 1.2: dimethylformamide / 12 h / 80 °C 2.1: aq. KOH / ethanol / 12 h / Heating 3.1: 36 percent / 150 °C View Scheme
参考文献
Sasse, Astrid; Ligneau, Xavier; Rouleau, Agnes; Elz, Sigurd; Ganellin, C. Robin; Arrang, Jean-Michel; Schwartz, Jean-Charles; Schunack, Walter; Stark, Holger
Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 4000 - 4010
反应条件
Yield given. Multistep reaction;
参考文献
Taber,D.F.; Ruckle,R.E.
Journal of the American Chemical Society, 1986 , vol. 108, p. 7686
反应条件
T=25°C; weitere Produkte: 2.2-Dimethyl-butan, Pentan;
参考文献
Schmerling
Journal of the American Chemical Society, 1945 , vol. 67, p. 1778
反应条件
aluminium trichloride T=22 - 40°C;
参考文献
Schmerling
Journal of the American Chemical Society, 1945 , vol. 67, p. 1778
反应条件
T=25°C; weitere Produkte: 2.2-Dimethyl-butan, Pentan;
参考文献
Schmerling
Journal of the American Chemical Society, 1945 , vol. 67, p. 1778
参考文献
Whitmore; Pietrusza; Sommer
Journal of the American Chemical Society, 1947 , vol. 69, p. 2109
参考文献
Whitmore; Pietrusza; Sommer
Journal of the American Chemical Society, 1947 , vol. 69, p. 2109
