4-氨基-3-丁烯-2-酮合成路线 (共 5 条)
参考文献
John Wyeth and Brother Limited
Patent: US3998831 A1, 1976 ;
反应条件
acetic acid in ethanol
Heating;
参考文献
Troschutz; Karger
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1815 - 1821
反应条件
pyridine; p-toluenesulfonyl chloride
1. Dimethylformamide, < 0 deg C 2. DMF, 2h; Yield given. Multistep reaction;
参考文献
Hoffman, Jacob M.; Phillips, Brian T.; Cochran, David W.
Journal of Organic Chemistry, 1984 , vol. 49, # 1 p. 193 - 195
反应条件
acetic acid in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethyl acetate; toluene
参考文献
Cassella Farbwerke Mainkur Aktiengesellschaft
Patent: US3969363 A1, 1976 ;
反应条件
ammonium acetate in ethanol
4 h; Heating;
参考文献
Fischer, Michael; Troschuetz, Reinhard
Synthesis, 2003 , # 10 p. 1603 - 1609