1-苯基-1-戊炔-3-醇合成路线 （共 20 条）
反应条件
zinc oxide T=120°C; 5 h; Neat (no solvent);
参考文献
Hosseini-Sarvari, Mona; Mardaneh, Zahra
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 12 p. 4297 - 4303
反应条件
diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in N,N-dimethyl-formamide T=85°C; 6 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; WATTERSON, Scott, Hunter; DYCKMAN, Alaric, J.; PITTS, William, J.; SPERGEL, Steven, H.
Patent: WO2010/85581 A1, 2010 ;
Location in patent: Page/Page column 86 ;
WO 2010/085581 A1
反应条件
1,4-diaza-bicyclo[2.2.2]octane in chloroform-d1 T=70°C; 0.5 h;
参考文献
Ogawa, Akiya; Sekiguchi, Masahito; Shibuya, Hiroaki; Kuniyasu, Hitoshi; Takami, Noriaki; et al.
Chemistry Letters, 1991 , # 10 p. 1805 - 1806
反应条件
ethanolamine in pentane T=25°C; 0.5 h;
参考文献
Brown, Herbert C.; Molander, Gary A.; Singh, Shankar M.; Racherla, Uday S.
Journal of Organic Chemistry, 1985 , vol. 50, # 10 p. 1577 - 1582
反应条件
hydrazine hydrate in ethanol T=3°C; Inert atmosphereReflux;
参考文献
Kolleth, Amandine; Christoph, Sarah; Arseniyadis, Stellios; Cossy, Janine
Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 85 p. 10511 - 10513,3
Title/Abstract Full Text Show Details
Kolleth, Amandine; Christoph, Sarah; Arseniyadis, Stellios; Cossy, Janine
Chemical Communications, 2012 , vol. 48, # 85 p. 10511 - 10513
反应条件
sodium nitrite in ethanol 24 h; Ambient temperature;
参考文献
Duranti, Ermanno; Balsamini, Cesarino; Spadoni, Gilberto; Staccioli, Lamberto
Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2870 - 2872
反应条件
tert.-butylhydroperoxide; oxygen; CuCl2*2H2O in tert-butyl alcohol T=70°C; P=760.051 Torr; Kinetics;
参考文献
Li; Wai Man Fong; Chao; Fung; Williams
Journal of Organic Chemistry, 2001 , vol. 66, # 11 p. 4087 - 4090
反应条件
1: 1.) LDA / 1.) THF, -60 deg C, 10 min, 2.) THF, 10 min 2: 86 percent / triethylamine, methanesulfonyl chloride / CH2Cl2 / 4.5 h / 0 - 20 °C 3: 1.) t-BuLi / 1.) THF, -78 deg C, 10 min, 2.) THF, from -78 deg C to -30 deg C, 10 min View Scheme
参考文献
Satoh, Tsuyoshi; Hayashi, Yasumasa; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 6 p. 1866 - 1869
反应条件
1: 86 percent / triethylamine, methanesulfonyl chloride / CH2Cl2 / 4.5 h / 0 - 20 °C 2: 1.) t-BuLi / 1.) THF, -78 deg C, 10 min, 2.) THF, from -78 deg C to -30 deg C, 10 min View Scheme
参考文献
Satoh, Tsuyoshi; Hayashi, Yasumasa; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 6 p. 1866 - 1869
反应条件
1: 100 percent / 30 percent H2O2 / CH2Cl2; H2O / 20 h / 20 °C 2: 91 percent / DABCO / CDCl3 / 0.5 h / 70 °C View Scheme
参考文献
Ogawa, Akiya; Sekiguchi, Masahito; Shibuya, Hiroaki; Kuniyasu, Hitoshi; Takami, Noriaki; et al.
Chemistry Letters, 1991 , # 10 p. 1805 - 1806
