4-羟基-n-甲基苯甲酰胺合成路线 （共 9 条）
反应条件
boron trifluoride diethyl etherate in diethyl ether T=20°C; Beckmann rearrangement; 1 h;
参考文献
Tokmadzhyan
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749
反应条件
hydroxylammonium sulfate T=80°C; 2.5 h;
参考文献
Cablewski, Teresa; Gurr, Paul A.; Raner, Kevin D.; Strauss, Christopher R.
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5814 - 5817
参考文献
Pharmacia Corporation
Patent: US2003/80320 A1, 2003 ;
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Hyatt, Stephen M.; Lockamy, Elizabeth L.; Stein, Rebecca A.; McDonnell, Donald P.; Miller, Aaron B.; Orband-Miller, Lisa A.; Willson, Timothy M.; Zuercher, William J.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 26 p. 6722 - 6724
参考文献
Merck and Co., Inc.
Patent: WO2003/104207 A2, 2003 ;
Location in patent: Page 54 ;
反应条件
zirconium(IV) dichloride oxide octahydrate 0.166667 h; Irradiation;
参考文献
Talukdar, Dhrubajyoti; Saikia, Lakhinath; Thakur, Ashim Jyoti
Synlett, 2011 , # 11 p. 1597 - 1601
反应条件
1: hydroxylamine hydrochloride; potassium carbonate / water / 1 h / 20 °C 2: boron trifluoride diethyl etherate / diethyl ether / 1 h / 20 °C View Scheme
参考文献
Tokmadzhyan
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749
反应条件
hydrogenchloride; acetic acid in water T=75°C; Retrobeckmann rearrangement; 10 h;
参考文献
Tokmadzhyan
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749
反应条件
sulfuric acid T=75°C; 10 h;
参考文献
Tokmadzhyan
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749
