5-甲醛基呋喃-2-硼酸合成路线 （共 52 条）
反应条件
1: With tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=-10 - 0°C; 1 h; 2: With hydrogenchloride in tetrahydrofuran; n-heptane; ethylbenzene; water T=30°C;
参考文献
Degussa AG
Patent: EP1403271 A1, 2004 ;
Location in patent: Page 3, 4 ;
反应条件
1: furfural diethyl acetal With biphenyl; 4-methyl-chlorobenzene; lithium in tetrahydrofuran T=-65°C; 9 h; 2: boric acid trimethyl ester in tetrahydrofuran T=-65°C; 1 h; 3: With hydrogenchloride in tetrahydrofuran; water pH=6.3;
参考文献
CLARIANT GMBH
Patent: WO2004/24738 A1, 2004 ;
Location in patent: Page/Page column 13 ;
反应条件
1: With biphenyl; boric acid trimethyl ester; lithium; isoprene in tetrahydrofuran T=22 - 25°C; 3.5 h; 2: With hydrogenchloride in tetrahydrofuran; water Product distribution / selectivity;
参考文献
Emmel, Ute; Rittmeyer, Peter; Wietelmann, Ulrich
Patent: US2009/131685 A1, 2009 ;
Location in patent: Page/Page column 9 ;
反应条件
sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water Suzuki coupling; 5 h; Heating;
参考文献
Mitsch, Andreas; Wissner, Pia; Silber, Katrin; Haebel, Peter; Sattler, Isabel; Klebe, Gerhard; Schlitzer, Martin
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 17 p. 4585 - 4600
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene T=100°C; Suzuki coupling; 4 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 36 p. 7402 - 7417
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium carbonate in ethylene glycol dimethyl ether; ethanol; water T=60°C; Suzuki-Miyaura Coupling; 2 h;
参考文献
Murasawa, Shinpei; Sato, Shinichi; Noguchi-Yachide, Tomomi; Hashimoto, Yuichi; Iuchi, Katsuya; Sodeoka, Mikiko; Dodo, Kosuke; Yokomatsu, Tsutomu; Aoyama, Hiroshi
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6384 - 6393,10
反应条件
caesium carbonate; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane T=95°C; Suzuki-Miyaura cross-coupling reaction; 91 h;
参考文献
Parry, Paul R.; Bryce, Martin R.; Tarbit, Brian
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 9 p. 1447 - 1449
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox; 2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol T=80°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / ethanol; water; ethylene glycol dimethyl ether / 2 h / 60 °C 2: sodium dihydrogenphosphate; 2-methyl-but-2-ene; sodium chlorite / water; tert-butyl alcohol / 11 h / 20 °C View Scheme
参考文献
Murasawa, Shinpei; Sato, Shinichi; Noguchi-Yachide, Tomomi; Hashimoto, Yuichi; Iuchi, Katsuya; Sodeoka, Mikiko; Dodo, Kosuke; Yokomatsu, Tsutomu; Aoyama, Hiroshi
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6384 - 6393,10
反应条件
sodium carbonate; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether T=85°C; Suzuki-Miyaura coupling; 9 h;
参考文献
Bulic, Bruno; Pickhardt, Marcus; Khlistunova, Inna; Biernat, Jacek; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Waldmann, Herbert
Angewandte Chemie - International Edition, 2007 , vol. 46, # 48 p. 9215 - 9219
