5-氯-1,3-二甲基-1H-吡唑-4-甲酸合成路线 （共 10 条）
反应条件
potassium permanganate; sodium carbonate in water T=60°C; 1 h;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
hydrogenchloride; sodium hydroxide in ethanol; water 2 h; Heating;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 29 percent / phosphoryl chloride / 2 h / Heating 2: 92 percent / NaOH / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
thionyl chloride T=79°C; 2 h;
参考文献
NIPPON SODA CO., LTD.
Patent: EP1362850 A1, 2003 ;
Location in patent: Page/Page column 40-41 ;
反应条件
hydrogen; sodium carbonate; palladium on activated charcoal in water P=1520 Torr; Ambient temperature;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 70 percent / conc. H2SO4 / 48 h / Heating 2: 93 percent / anhydrous sodium acetate, H2 / 5percent Pd/C / ethanol / 1520 Torr / Ambient temperature View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature 2: Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature 2: thionyl chloride / Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
sulfuric acid
48 h; Heating;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
