2-(4,4,5,5-四甲基-1,3,2-二杂氧戊硼烷-2-基)苯酚合成路线 （共 15 条）
反应条件
1: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane T=80°C; 17 h; 2: 2-iodophenol; 4,4,5,5-tetramethyl-[1,3,2]dioxaborolane in 1,4-dioxane T=80°C; 6 h;
参考文献
Commonwealth Scientific and Industrial Research Organisation
Patent: US6680401 B1, 2004 ;
Location in patent: Page column 67 ;
反应条件
in toluene T=130°C; 25 h; Dean-StarkInert atmosphere;
参考文献
Friedman, Adam A.; Panteleev, Jane; Tsoung, Jennifer; Huynh, Vaizanne; Lautens, Mark
Angewandte Chemie - International Edition, 2013 , vol. 52, # 37 p. 9755 - 9758
反应条件
tert.-butylnitrite in acetonitrile T=80°C; 2 h;
参考文献
Qiu, Di; Jin, Liang; Zheng, Zhitong; Meng, He; Mo, Fanyang; Wang, Xi; Zhang, Yan; Wang, Jianbo
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1923 - 1933
反应条件
LiOH*H2O; palladium diacetate; 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran; water T=20°C; Suzuki-Miyaura coupling; 2 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Tetrahedron, 2010 , vol. 66, # 1 p. 297 - 303
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / -78 °C / |Inert atmosphere 2: tert.-butyl lithium / diethyl ether; pentane / 0.5 h / -78 - 25 °C / |Inert atmosphere View Scheme
参考文献
Sumida, Yuto; Kato, Tomoe; Hosoya, Takamitsu
Organic Letters, 2013 , vol. 15, # 11 p. 2806 - 2809
反应条件
LiOH*H2O; palladium diacetate; 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran; water T=20°C; Suzuki-Miyaura coupling; 2 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Tetrahedron, 2010 , vol. 66, # 1 p. 297 - 303
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / -78 °C / |Inert atmosphere 2: sec.-butyllithium / hexane; diethyl ether; cyclohexane / 0.5 h / -78 - 25 °C / |Inert atmosphere View Scheme
参考文献
Sumida, Yuto; Kato, Tomoe; Hosoya, Takamitsu
Organic Letters, 2013 , vol. 15, # 11 p. 2806 - 2809
反应条件
hydrogenchloride; polystyrene boronic acid in acetonitrile T=20°C; 18 h;
参考文献
Tetrahedron Letters, , vol. 45, # 35 p. 6657 - 6660
反应条件
lithium hydroxide; palladium diacetate in tetrahydrofuran; water T=20°C; Suzuki-Miyaura cross-coupling; 2 h;
参考文献
Ishikawa, Shunpei; Manabe, Kei
Chemical Communications, 2006 , # 24 p. 2589 - 2591
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in water; acetonitrile T=50°C; Suzuki coupling; 20 h;
参考文献
Journal of Organic Chemistry, , vol. 73, # 7 p. 2951 - 2954
