2,5-二羟基苯基乙酸GAMMA内酯合成路线 （共 19 条）
反应条件
pyridine hydrochloride T=180 - 190°C; 3 h;
参考文献
Venkateswarlu, Somepalli; Panchagnula, Gopala K.; Guraiah, Mothukuri Bala; Subbaraju, Gottumukkala V.
Tetrahedron, 2006 , vol. 62, # 42 p. 9855 - 9860
反应条件
hydrogenchloride in tetrahydrofuran; water 5 h; Ambient temperature;
参考文献
Takahata, Hiroki; Anazawa, Akira; Moriyama, Keiko; Yamazaki, Takao
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1501 - 1504
反应条件
1,4-dioxane; hydrogen bromide
参考文献
McElvain; Engelhardt
Journal of the American Chemical Society, 1944 , vol. 66, p. 1077,1082
参考文献
McElvain; Engelhardt
Journal of the American Chemical Society, 1944 , vol. 66, p. 1077,1082
反应条件
1.1: sulfur; morpholine; p-toluenesulfonic acid / 8 h / 120 - 130 °C 1.2: 64 percent / sodium hydroxide; tetrabutylammonium bromide / H2O / 8 h / 100 °C 2.1: 85 percent / phosphorus oxychloride / 1,2-dichloro-ethane / 16 h / 20 °C 3.1: 66 percent / pyridine hydrochloride / 3 h / 180 - 190 °C View Scheme
参考文献
Venkateswarlu, Somepalli; Panchagnula, Gopala K.; Guraiah, Mothukuri Bala; Subbaraju, Gottumukkala V.
Tetrahedron, 2006 , vol. 62, # 42 p. 9855 - 9860
反应条件
1: 85 percent / phosphorus oxychloride / 1,2-dichloro-ethane / 16 h / 20 °C 2: 66 percent / pyridine hydrochloride / 3 h / 180 - 190 °C View Scheme
参考文献
Venkateswarlu, Somepalli; Panchagnula, Gopala K.; Guraiah, Mothukuri Bala; Subbaraju, Gottumukkala V.
Tetrahedron, 2006 , vol. 62, # 42 p. 9855 - 9860
参考文献
Wolkowitz; Dunn
Biochemical Preparations, 1955 , vol. 4, p. 6,11
Full Text Show Details
Abbott; Smith
Journal of Biological Chemistry, 1949 , vol. 179, p. 365,367
参考文献
Ozaki, Yutaka; Quan, Zhe-Shan; Watabe, Kyouko; Kim, Sang-Won
Heterocycles, 1999 , vol. 51, # 4 p. 727 - 731
反应条件
1: 45 percent / toluene / 15 h / Heating 2: 78 percent / 10percent HCl / tetrahydrofuran; H2O / 5 h / Ambient temperature View Scheme
参考文献
Takahata, Hiroki; Anazawa, Akira; Moriyama, Keiko; Yamazaki, Takao
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1501 - 1504
参考文献
Wolkow; Baumann
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1891 , vol. 15, p. 243,244
