1: With hydrogenchloride; Trizma Base; threo-1,4-dimercapto-2,3-butanediol; N-methyltransferase in water T=30°C; pH=8.0; 0.5 h; 2: With trichloroacetic acid in water Kinetics;
参考文献
UNIVERSITY OF FLORIDA
Patent: WO2004/13092 A2, 2004 ;
Location in patent: Page 32; 35-36; 42-43 ;
1: With cyclopenta-1,3-diene in water T=20°C; Addition; methylation; 16 h; 2: With triethylsilane; trifluoroacetic acid in chloroform T=20°C; Hydrolysis; 6 h;
Baxter, Nicholas J.; Rigoreau, Laurent J. M.; Laws, Andrew P.; Page, Michael I.
Journal of the American Chemical Society, 2000 , vol. 122, # 14 p. 3375 - 3385