2-O-(对硝基苯基)-alpha-d-正乙酰基神经氨酸合成路线 （共 10 条）
反应条件
lithium hydroxide in methanol; water T=20°C; Hydrolysis; 1 h;
参考文献
Sun, Xue-Long; Kanie, Yoshimi; Guo, Chao-Tan; Kanie, Osamu; Suzuki, Yasuo; Wong, Chi-Huey
European Journal of Organic Chemistry, 2000 , # 14 p. 2643 - 2653
反应条件
sodium hydroxide 0.5 h; Ambient temperature;
参考文献
Eschenfelder; Brossmer
Carbohydrate research, 1987 , vol. 162, # 2 p. 294 - 297
反应条件
1: 60 percent / aq. NaOH / benzyltriethylammonium chloride / CHCl3 / 0.5 h / Heating 2: 1.) sodium methoxide, 2.) aq. NaOH / 1.) MeOH, RT, 2 h; 2.) RT, 0.5 h View Scheme
参考文献
Rothermel, Joerg; Faillard, Hans
Carbohydrate Research, 1990 , vol. 196, # 1 p. 29 - 40
反应条件
1: 60 percent / aq. NaOH / benzyltriethylammonium chloride / CHCl3 / 0.5 h / Heating 2: 1.) sodium methoxide, 2.) aq. NaOH / 1.) MeOH, RT, 2 h; 2.) RT, 0.5 h View Scheme
参考文献
Rothermel, Joerg; Faillard, Hans
Carbohydrate Research, 1990 , vol. 196, # 1 p. 29 - 40
反应条件
1: 76 percent / dimethylformamide / 12 h / 20 °C 2: 82 percent / 4-(dimethylamino)pyridine / acetonitrile / 2 h / 20 °C 3: 92 percent / nBu3SnH; AIBN / toluene / 1 h / 110 °C 4: 94 percent / LiOH*H2O / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Eschenfelder; Brossmer
Carbohydrate research, 1987 , vol. 162, # 2 p. 294 - 297
反应条件
1: 76 percent / dimethylformamide / 12 h / 20 °C 2: 82 percent / 4-(dimethylamino)pyridine / acetonitrile / 2 h / 20 °C 3: 92 percent / nBu3SnH; AIBN / toluene / 1 h / 110 °C 4: 94 percent / LiOH*H2O / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Sun, Xue-Long; Kanie, Yoshimi; Guo, Chao-Tan; Kanie, Osamu; Suzuki, Yasuo; Wong, Chi-Huey
European Journal of Organic Chemistry, 2000 , # 14 p. 2643 - 2653
反应条件
1: 82 percent / 4-(dimethylamino)pyridine / acetonitrile / 2 h / 20 °C 2: 92 percent / nBu3SnH; AIBN / toluene / 1 h / 110 °C 3: 94 percent / LiOH*H2O / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Sun, Xue-Long; Kanie, Yoshimi; Guo, Chao-Tan; Kanie, Osamu; Suzuki, Yasuo; Wong, Chi-Huey
European Journal of Organic Chemistry, 2000 , # 14 p. 2643 - 2653
反应条件
1: 92 percent / nBu3SnH; AIBN / toluene / 1 h / 110 °C 2: 94 percent / LiOH*H2O / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Sun, Xue-Long; Kanie, Yoshimi; Guo, Chao-Tan; Kanie, Osamu; Suzuki, Yasuo; Wong, Chi-Huey
European Journal of Organic Chemistry, 2000 , # 14 p. 2643 - 2653
反应条件
1: 57 percent / dimethylformamide / 12 h / Ambient temperature 2: 71 percent / M sodium methoxide / methanol / 1 h / Ambient temperature 3: 87 percent / 0.1 M sodium hydroxide / 0.5 h / Ambient temperature View Scheme
参考文献
Eschenfelder; Brossmer
Carbohydrate research, 1987 , vol. 162, # 2 p. 294 - 297
反应条件
4-methyl-morpholine in water T=75°C; pH=8.50; Kinetics; Further Variations:Temperatures;
参考文献
Dookhun, Veedeeta; Bennet, Andrew J.
Journal of the American Chemical Society, 2005 , vol. 127, # 20 p. 7458 - 7465
