1,4-二羟基-2-甲基蒽-9,10-二酮合成路线 （共 22 条）
反应条件
sodium tetrahydroborate; boron trifluoride diethyl etherate in diethylene glycol dimethyl ether 1.) room temp. to 40 deg C, 2.) 30 min;
参考文献
Laatssh, Hartmut; Schmidt, Andreas Johann
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1993 , vol. 48, # 9 p. 1291 - 1294
反应条件
1: With AlCl3, aluminium chloride; sodium chloride
T=200°C; 0.05 h;
2: With hydrogenchloride in water
T=100°C; 2 h;
参考文献
Khoumeri, Omar; Montana, Marc; Terme, Thierry; Vanelle, Patrice
Tetrahedron, 2008 , vol. 64, # 49 p. 11237 - 11242
反应条件
1: 3-(phenylsulfanyl)isobenzofuran-1(3H)-one With lithium tert-butylate in tetrahydrofuran
T=-60°C; 0.416667 h;
2: monomethyl-1,4-benzoquinone in tetrahydrofuran
T=-60 - 20°C; Hauser annulation; Further stages.;
参考文献
Mal, Dipakranjan; Ray, Sutapa; Sharma, Indrajeet
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4981 - 4984
反应条件
aluminium trichloride in nitrobenzene
T=80°C; 0.25 h;
参考文献
Sartori, Giovanni; Casnati, Giuseppe; Bigi, Franca; Robles, Pasquale
Tetrahedron Letters, 1987 , vol. 28, # 14 p. 1533 - 1536
反应条件
aluminium trichloride in nitrobenzene
T=80°C; 0.5 h;
参考文献
Sartori, Giovanni; Casnati, Giuseppe; Bigi, Franca; Foglio, Federica
Gazzetta Chimica Italiana, 1990 , vol. 120, # 1 p. 13 - 19
反应条件
piperidinium acetate in ethanol
Heating;
参考文献
Bingham, Steve J.; Tyman, John H. P.; Malik, K. M. A.; Hibbs, David E.; Hursthouse, Michael B.
Journal of Chemical Research, Miniprint, 1998 , # 9 p. 2465 - 2496
反应条件
in benzene
138 h; Ambient temperature;
参考文献
Simoneau; Brassard
Tetrahedron, 1988 , vol. 44, # 4 p. 1015 - 1022
反应条件
potassium hydroxide in ethanol
22 h; Heating;
参考文献
Boddy, Ian K.; Boniface, Peter J.; Cambie, Richard C.; Craw, Peter A.; Huang, Zhen-Dong; et al.
Australian Journal of Chemistry, 1984 , vol. 37, # 7 p. 1511 - 1529
反应条件
1: 86 percent / triethylamine / dimethylsulfoxide / 4 h / Ambient temperature
2: 76 percent / 10percent aq. NaOH / dioxane / 2 h / 80 °C
3: 86 percent / quinoline / 120 °C
View Scheme
参考文献
Gorelik, M. V.; Mishina, E. V.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 533 - 540
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 3 p. 607 - 615
反应条件
1.1: PhI(OAc)2 / methanol
1.2: Acid hydrolysis
2.1: LiOt-Bu / tetrahydrofuran / 0.42 h / -60 °C
2.2: 65 percent / tetrahydrofuran / -60 - 20 °C
View Scheme
参考文献
Mal, Dipakranjan; Ray, Sutapa; Sharma, Indrajeet
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4981 - 4984
