3-(1H-吡唑-1-基)苯甲腈合成路线 （共 4 条）
反应条件
caesium carbonate; copper(I) bromide in dimethyl sulfoxide T=80°C; Ullmann coupling; 24 h;
参考文献
Yang, Minghua; Liu, Fei
Journal of Organic Chemistry, 2007 , vol. 72, # 23 p. 8969 - 8971
反应条件
1: 3-(1H-pyrazol-1-yl)aniline With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 2: copper (I) cyanide; potassium cyanide in water T=60°C; 0.333333 h;
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
反应条件
1.1: 68 percent / hydrazine hydrate / Pd/C / ethanol / 1 h / Heating 2.1: NaNO2; HCl / H2O / 0 - 5 °C 2.2: 64 percent / CuCN / H2O / 0.33 h / 60 °C View Scheme
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
反应条件
1.1: 84 percent / ethanol / 1 h / Heating 2.1: 68 percent / hydrazine hydrate / Pd/C / ethanol / 1 h / Heating 3.1: NaNO2; HCl / H2O / 0 - 5 °C 3.2: 64 percent / CuCN / H2O / 0.33 h / 60 °C View Scheme
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
