(4S)-2,5-二氧代-4-(苯基甲基)-3-恶唑烷羧酸苄酯合成路线 （共 4 条）
反应条件
4-methyl-morpholine in tetrahydrofuran T=2 - 5°C; 2 h; Yield given;
参考文献
Fuller; Cohen; Shabankareh; Blair; Goodman; Naider
Journal of the American Chemical Society, 1990 , vol. 112, # 20 p. 7414 - 7416
反应条件
1: 4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester With ethanol; O-propargylquinidine in diethyl ether T=20°C; 0.25 h; Molecular sieve; 2: ethanol in diethyl ether T=-60°C; 20 h; Reagent/catalyst; enantioselective reaction;
参考文献
Ishii, Yutaka; Fujimoto, Ryosuke; Mikami, Masafumi; Murakami, Satoshi; Miki, Yasushi; Furukawa, Yoshiro
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 609 - 615
反应条件
1: 4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester With ethanol; O-propargylquinine in diethyl ether T=20°C; 0.25 h; Molecular sieve; 2: ethanol in diethyl ether T=-60°C; 20 h; Reagent/catalyst; enantioselective reaction;
参考文献
Ishii, Yutaka; Fujimoto, Ryosuke; Mikami, Masafumi; Murakami, Satoshi; Miki, Yasushi; Furukawa, Yoshiro
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 609 - 615
反应条件
Li(Et3CO)3AlH in tetrahydrofuran T=0°C;
参考文献
Fehrentz, Jean-Alain; Pothion, Catherine; Califano, Jean-Christophe; Loffet, Albert; Martinez, Jean
Tetrahedron Letters, 1994 , vol. 35, # 48 p. 9031 - 9034
