2,3-二氧代吲哚啉-5-甲酸合成路线 （共 15 条）
反应条件
sulfuric acid T=50 - 55°C; 0.5 h; Inert atmosphere;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 292 - 302
反应条件
hydrogen bromide T=190°C;
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3579
反应条件
hydrogenchloride in water T=150°C; 0.0833333 h; Microwave irradiation;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 16 p. 4948 - 4956
反应条件
sulfuric acid T=90°C; 0.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 12 p. 3440 - 3443
反应条件
1: hydroxylamine hydrochloride; Na2SO4; H2SO4 / H2O / Heating 2: H2SO4 / 0.5 h / 90 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 12 p. 3440 - 3443
反应条件
1: NH2OH+HCl 2: concentrated sulfuric acid 3: aqueous HBr / 190 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3579
反应条件
1: concentrated sulfuric acid 2: aqueous HBr / 190 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 73, p. 3579
反应条件
1: hydroxylamine hydrochloride; sodium sulfate; aq. HCl / 55 °C 2: 45 percent / conc. sulfuric acid / 55 - 80 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 1 p. 21 - 39
反应条件
1: With sulfuric acid; hydroxylamine hydrochloride 2: With sulfuric acid T=90°C;
参考文献
Tetrahedron, , vol. 67, # 35 p. 6713 - 6729
反应条件
anhydrous iron chloride
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 12 p. 4509 - 4515
