1: With trichlorophosphate T=100°C; 2 h; 2: With water T=20°C; 3: With sodium hydroxide in water pH=8;

trichlorophosphate in N,N-dimethyl-formamide T=0 - 70°C;

hydrogenchloride in methanol 16 h; Ambient temperature;

1: 4-bromo-1-methyl-1H-pyrazole With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-78 - 20°C; 1 h;

暂无反应条件数据

1: With Jone's reagent in acetone T=40°C; 2: With sodium hydroxide in water; acetone pH=4;

in acetone

1.1: potassium tert-butylate / ethylene glycol dimethyl ether / 0.67 h / -60 - -55 °C 1.2: -55 - 85 °C 2.1: potassium tert-butylate / ethylene glycol dimethyl ether / 18 h / 85 °C / |Sealed tube 3.1: hydrazine monohydrochloride / ethanol / 15 h / 90 °C 3.2: |Cooling 4.1: ethanol / 18 h / 45 °C 5.1: N-bromosuccinmide / dichloromethane; acetonitrile 6.1: trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C 6.2: 4 h / 20 °C View Scheme

1: sodium tetrahydroborate; methanol / 1 h / 0 - 20 °C 2: thionyl chloride / dichloromethane / 3 h / 0 - 20 °C View Scheme

1: potassium hydroxide; hydroxylamine hydrochloride / ethanol; water 2: acetic anhydride / 1 h / |Reflux View Scheme