N-乙酰-2,3-二脱氢-2-脱氧神经氨酸合成路线 （共 9 条）
反应条件
in N,N-dimethyl-formamide T=105°C; 6 h;
参考文献
WO2010/127443 A1, ;
Page/Page column 31-32 ;
WO 2010/127443 A1
反应条件
barium dihydroxide; water T=90°C; Hydrolysis; 18 h;
参考文献
Wilson, Jennifer C.; Thomson, Robin J.; Dyason, Jeffrey C.; Florio, Pas; Quelch, Kaylene J.; Abo, Samia; Von Itzstein, Mark
Tetrahedron Asymmetry, 2000 , vol. 11, # 1 p. 53 - 73
反应条件
methanol; sodium methylate 0.5 h; Ambient temperature;
参考文献
Baggett; Marsden
Carbohydrate research, 1982 , vol. 110, # 1 p. 11 - 18
反应条件
potassium hydroxide in methanol T=20°C; 12 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 16, # 14 p. 6783 - 6788
反应条件
1: 62 percent / triethylamine / CH2Cl2 / 1 h 2: sodium methoxide (1 M) / methanol / 1.5 h 3: NaOH (0.1 N) / methanol; H2O / 1 h View Scheme
参考文献
Carbohydrate research, , vol. 186, # 2 p. 326 - 334
反应条件
sodium hydroxide in methanol; water 1 h; Yield given;
参考文献
Carbohydrate research, , vol. 186, # 2 p. 326 - 334
反应条件
4-methyl-morpholine in water T=75°C; pH=8.50; Kinetics; Further Variations:Temperatures;
参考文献
Journal of the American Chemical Society, , vol. 127, # 20 p. 7458 - 7465
反应条件
4-methyl-morpholine T=75°C; pH=1.00; Kinetics; Further Variations:TemperaturespH-values;
参考文献
Journal of the American Chemical Society, , vol. 127, # 20 p. 7458 - 7465
反应条件
NanC sialidase from Streptococcus pneumoniae in water-d2 T=20°C; pH=7; aq. phosphate bufferEnzymatic reaction; KineticsMechanism; ConcentrationpH-valueSolventReagent/catalyst;
参考文献
Journal of the American Chemical Society, , vol. 133, # 6 p. 1718 - 1721
