N,N-二甲基甘氨酸盐酸盐合成路线 （共 8 条）
反应条件
1: in water T=25 - 55°C; 11 h; 2: With hydrogenchloride in water T=40°C;
参考文献
US6875890 B1, ;
Page/Page column 3 ;
反应条件
hydrogenchloride 24 h; Heating;
参考文献
Gate; Threadgill; Stevens; Chubb; Vickers; Langdon; Hickman; Gescher
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1046 - 1052
反应条件
hydrogenchloride in ethanol; water; acetone
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 10 p. 3021 - 3025
反应条件
dicyclohexyl-carbodiimide
参考文献
Yurkevich,A.M. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 1267 - 1272,1201 - 1204
参考文献
Bergel; Bolz
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1933 , vol. 215, p. 27,28
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1933 , vol. 220, p. 23
反应条件
in ethanol; dichloromethane; nitrogen
参考文献
Bhagwat, Shripad S.; Satoh, Yoshitaka; Sakata, Steven T.; Buhr, Chris A.; Albers, Ronald; Sapienza, John; Plantevin, Veronique; Chao, Qi; Sahasrabudhe, Kiran; Ferri, Rachel; Narla, Rama K.
Patent: US2005/9876 A1, 2005 ;
US 20050009876 A1
反应条件
thionyl chloride
T=78°C; 0.5 h;
参考文献
Sum, Phaik-Eng; Lee, Ving J.; Testa, Raymond T.; Hlavka, Joseph J.; Ellestad, George A.; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 1 p. 184 - 188
反应条件
phosphorus pentachloride; acetyl chloride
参考文献
Vasil'eva,Z.A.; Petrun'kin,V.E.
Pharmaceutical Chemistry Journal, 1969 , # 9 p. 516 - 518
Khimiko-Farmatsevticheskii Zhurnal, 1969 , # 9 p. 27 - 29
