2-[3-(1-丙烯基)]萘合成路线 （共 25 条）
反应条件
1: 2-bromo-naphthalene With iodine; magnesium in tetrahydrofuran
Inert atmosphereReflux;
2: allyl bromide in tetrahydrofuran
T=20°C; Reflux;
3: With ammonium chloride in tetrahydrofuran
T=20°C;
参考文献
Blanco, Beatriz; Sedes, Anti; Peon; Lamb, Heather; Hawkins, Alastair R.; Castedo, Luis; Gonzalez-Bello, Concepcion
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 18 p. 3662 - 3676
反应条件
18-crown-6 ether; cesium fluoride in acetonitrile
T=100°C; 5 h;
参考文献
Kim, D. W.; Choe, Y. S.; Chi, D. Y.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S89 - S89
反应条件
indium; triphenylphosphine; lithium chloride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in N,N-dimethyl-formamide
T=100°C; 1 h;
参考文献
Lee, Kooyeon; Kim, Hyunseok; Mo, Juntae; Lee, Phil Ho
Chemistry - An Asian Journal, 2011 , vol. 6, # 8 p. 2147 - 2157
反应条件
indium(III) chloride; indium; lithium chloride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide
T=100°C; 2 h;
参考文献
Seomoon, Dong; Phil, Ho Lee
Journal of Organic Chemistry, 2008 , vol. 73, # 3 p. 1165 - 1168
反应条件
indium(III) chloride; indium; lithium chloride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide
T=100°C; 2 h;
参考文献
Seomoon, Dong; Phil, Ho Lee
Journal of Organic Chemistry, 2008 , vol. 73, # 3 p. 1165 - 1168
反应条件
bis(η3-allyl-μ-chloropalladium(II)) in ethylene glycol dimethyl ether
T=85°C; 9 h; Inert atmosphere;
参考文献
Denmark, Scott E.; Werner, Nathan S.
Journal of the American Chemical Society, 2008 , vol. 130, # 48 p. 16382 - 16393
反应条件
diisobutylaluminium hydride; triphenylphosphine; bis(acetylacetonate)nickel(II) in ethylene glycol dimethyl ether; hexane
T=80°C; 24 h;
参考文献
Shirakawa, Eiji; Yamasaki, Kenji; Hiyama, Tamejiro
Synthesis, 1998 , # 10 p. 1544 - 1549
反应条件
triphenyl phosphite; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in 1,4-dioxane
T=80°C; Suzuki-Miyaura coupling; 2 h;
参考文献
Kayaki, Yoshihito; Koda, Takashi; Ikariya, Takao
European Journal of Organic Chemistry, 2004 , # 24 p. 4989 - 4993
反应条件
potassium tert-butylate; 1-n-butyl-3-methylimidazolium tetrafluoroborate in acetonitrile
T=70°C; 0.416667 h;
参考文献
Kim, Dong Wook; Song, Choong Eui; Chi, Dae Yoon
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4281 - 4285
反应条件
1: With NiBr2(PPh3)2; magnesium bromide in tetrahydrofuran; toluene
T=20 - 60°C; Inert atmosphere;
2: With ammonium chloride in tetrahydrofuran; water; toluene
参考文献
Sumida, Yuto; Yorimitsu, Hideki; Oshima, Koichiro
Organic Letters, 2010 , vol. 12, # 10 p. 2254 - 2257
