4-氨基-2-甲氧基苯甲酸合成路线 （共 20 条）
反应条件
hydrogen; palladium on activated charcoal in methanol P=1551.49 Torr;
参考文献
Chakravarty, Sarvajit; Dugar, Sundeep; Lu, Qing; Luedtke, Gregory R.; Mavunkel, Babu J.; Perumattam, John J.; Tester, Richland W.
Patent: US2004/142940 A1, 2004 ;
Location in patent: Page/Page column 69-70 ;
US 20040142940 A1
反应条件
sodium hydroxide in ethanol 0.666667 h; Heating;
参考文献
Hewlett, William A.; De Paulis, Tomas; Mason, N. Scott; Schmidt, Dennis E.; Trivedi, Bakula L.; Zhang, Zhang-Jin; Ebert, Michael H.
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 12 p. 2079 - 2084
反应条件
sodium hydroxide 3 h; Heating;
参考文献
Barraclough, P.; Beams, R. M.; Black, J. W.; Cambridge, D.; Collard, D.; et al.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 6 p. 467 - 477
反应条件
1: aq.-ethanolic Na2CO3 2: iron-powder; aq.-ethanolic HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 592,595
反应条件
1: aqueous H2SO4 / anschliessendes Erwaermen mit wss. NaNO2 2: iron-powder; aq.-ethanolic HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 592,595
反应条件
1.1: sulfuric acid / ethanol / 4 h / 50 °C / Inert atmosphere 2.1: potassium carbonate / acetone / 5 h / Reflux 3.1: water; sodium hydroxide / methanol / 2.5 h / Reflux 3.2: pH 7 View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 24 p. 7377 - 7381
反应条件
1.1: potassium carbonate / acetone / 5 h / Reflux 2.1: water; sodium hydroxide / methanol / 2.5 h / Reflux 2.2: pH 7 View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 24 p. 7377 - 7381
反应条件
1.1: sulfuric acid / 6 h / Reflux 2.1: sulfuric acid / ethanol / 4 h / 50 °C / Inert atmosphere 3.1: potassium carbonate / acetone / 5 h / Reflux 4.1: water; sodium hydroxide / methanol / 2.5 h / Reflux 4.2: pH 7 View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 24 p. 7377 - 7381
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 578,586
反应条件
1: aqueous KMnO4 2: H2SO4 View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 578,586
