1: 75 percent / N-bromosuccinimide (NBS), AIBN / CCl4; CHCl3 / 1.5 h / Irradiation 2: 95 percent / 3 h / 100 °C 3: 1.) sodium borohydride, 2.) 1 N aq. HCl / 1.) 2-propanol, water, RT, 3 h, 2.) ethanol, 75 deg C, 1 h View Scheme
参考文献
Bigge, Christopher F.; Johnson, Graham; Ortwine, Daniel F.; Drummond, James T.; Retz, Daniel M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 8 p. 1371 - 1384