4-氨基-2-氯苯甲酸合成路线

参考文献

FUJISAWA PHARMACEUTICAL CO., LTD.
Patent: EP1142879 A1, 2001 ;

参考文献

Madsen, Peter; Ling, Anthony; Plewe, Michael; Sams, Christian K.; Knudsen, Lotte B.; Sidelmann, Ulla G.; Ynddal, Lars; Brand, Christian L.; Andersen, Birgitte; Murphy, Douglas; Teng, Min; Truesdale, Larry; Kiel, Dan; May, John; Kuki, Atsuo; Shi, Shenghua; Johnson, Michael D.; Teston, Kimberly Ann; Feng, Jun; Lakis, James; Anderes, Kenna; Gregor, Vlad; Lau, Jesper
Journal of Medicinal Chemistry, 2002 , vol. 45, # 26 p. 5755 - 5775

2457-76-34-氨基-2-氯苯甲酸

34436-50-52-二甲基氨基乙基4-丁基氨基-2-氯苯甲酸酯

参考文献

Childress et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 3988,3991

64-17-5乙醇+

2457-76-34-氨基-2-氯苯甲酸

118-91-22-氯苯甲酸

参考文献

Tiemann
Chemische Berichte, 1891 , vol. 24, p. 706

2457-76-34-氨基-2-氯苯甲酸

116209-31-5

参考文献

Gangjee, Aleem; Jain, Hiteshkumar D.; McGuire, John J.; Kisliuk, Roy L.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6730 - 6739

2457-76-34-氨基-2-氯苯甲酸

211374-81-14-氨基-2-氯苯甲酰胺

参考文献

Sumitomo Pharmaceuticals Company, Limited
Patent: EP1500643 A1, 2005 ;
Location in patent: Page 30-31 ;
EP 1500643 A1

2457-76-34-氨基-2-氯苯甲酸

81542-91-8

参考文献

Gangjee, Aleem; Jain, Hiteshkumar D.; McGuire, John J.; Kisliuk, Roy L.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6730 - 6739

2457-76-34-氨基-2-氯苯甲酸+

137-07-52-氨基苯硫醇

43088-00-24-苯并噻唑-2-基-3-氯苯胺

参考文献

Tasler, Stefan; Mueller, Oliver; Wieber, Tanja; Herz, Thomas; Pegoraro, Stefano; Saeb, Wael; Lang, Martin; Krauss, Rolf; Totzke, Frank; Zirrgiebel, Ute; Ehlert, Jan E.; Kubbutat, Michael H.G.; Schaechtele, Christoph
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6728 - 6737

2457-76-34-氨基-2-氯苯甲酸

50687-71-32-氯-4-羟基苯甲酸 4-戊基苯基酯

参考文献

Kamogawa, Hiroyoshi; Hirose, Tomoki; Nanasawa, Masato
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2457-76-34-氨基-2-氯苯甲酸

61953-04-62-氯-4-(氯磺酰基)苯甲酸

参考文献

Genetech, Inc.; Curis, Inc.; Cai, Xiong; Qian, Changgeng; Zhai, Haixiao
Patent: US2014/18368 A1, 2014 ;
Location in patent: Paragraph 0162; 0188 ;