bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine in tetrahydrofuran Addition;

1.1: thionyl chloride / 5 h / 70 °C / |Inert atmosphere 1.2: 4 h / |Reflux; |Inert atmosphere 2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / tetrahydrofuran / 10 h / |Reflux; |Inert atmosphere View Scheme

1.1: thionyl chloride / 5 h / 70 °C / |Inert atmosphere 1.2: 4 h / |Reflux; |Inert atmosphere 2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / tetrahydrofuran / 10 h / |Reflux; |Inert atmosphere View Scheme

Sonogashira coupling;