2-氯-1-(5-氯-2-羟基苯基)乙酮合成路线 （共 5 条）
反应条件
1: T=80°C; 2.5 h; 2: With AlCl3, aluminium chloride T=30 - 130°C; 15.5 h; 3: With hydrogenchloride; water T=60°C; 0.25 h;
参考文献
DECODE CHEMISTRY, INC.; SINGH, Jasbir; GURNEY, Mark E.
Patent: WO2005/123724 A1, 2005 ;
Location in patent: Page/Page column 81 ;
反应条件
aluminium trichloride T=140 - 150°C;
参考文献
Bourdon,R.; Ranisteano-Bourdon,S.
Chimica Therapeutica, 1971 , vol. 6, p. 93 - 100
反应条件
hydrogenchloride; aluminium trichloride; boron trichloride 1) 20 h, 1,2-dichloroethane, 2) 30 min; Yield given. Multistep reaction;
参考文献
Toyoda, Tatsuo; Sasakura, Kazuyuki; Sugasawa, Tsutomu
Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 189 - 191
反应条件
1: 130 - 140 °C 2: AlCl3 / 140 - 150 °C View Scheme
参考文献
Bourdon,R.; Ranisteano-Bourdon,S.
Chimica Therapeutica, 1971 , vol. 6, p. 93 - 100
反应条件
sodium acetate in ethanol 0.166667 h; Heating / reflux;
参考文献
DECODE CHEMISTRY, INC.; SINGH, Jasbir; GURNEY, Mark E.
Patent: WO2005/123724 A1, 2005 ;
Location in patent: Page/Page column 81 ;
