N-[4-羟基-3-(1-氧代-3-苯基烯丙基)苯基]乙酰胺合成路线 (共 4 条)
反应条件
1: With sodium hydroxide in ethanol; water T=20°C; 6 h; 2: With acetic acid in ethanol; water 1 h; Cooling with ice;
参考文献
The University of Melbourne
Patent: US7863323 B1, 2011 ;
Location in patent: Page/Page column 17; 23; 24 ;
反应条件
1: AlCl3, aluminium chloride / nitrobenzene / |Reflux 2: potassium hydroxide / ethanol / 12 h / 30 °C View Scheme
参考文献
Moorkoth, Sudheer; Srinivasan; Gopalan Kutty; Joseph, Alex; Naseer
Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 5066 - 5075
反应条件
iodine in dimethyl sulfoxide 0.5 h; Heating;
参考文献
Agrawal, Nitin N.; Soni
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 12 p. 2601 - 2603
反应条件
1: iodine / dimethyl sulfoxide / 0.5 h / Microwave irradiation
2: sulfuric acid / ethanol / 0.5 h / Microwave irradiation
View Scheme
参考文献
Moorkoth, Sudheer; Srinivasan; Gopalan Kutty; Joseph, Alex; Naseer
Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 5066 - 5075