1-(2-甲基苯基)-2-吡咯里嗪酮合成路线 （共 10 条）
反应条件
potassium phosphate; copper(l) iodide in dimethyl sulfoxide T=110°C; Goldberg-type N-arylation; 5 h;
参考文献
Wang, Chaoyu; Liu, Lijuan; Wang, Wei; Ma, Dong-Sheng; Zhang, Hua
Molecules, 2010 , vol. 15, # 3 p. 1154 - 1160
反应条件
manganese(III) fluoride; palladium diacetate; acetic acid in 2,2,2-trifluoroethanol; water T=40°C; 2 h;
参考文献
Neufeldt, Sharon R.; Seigerman, Cydney K.; Sanford, Melanie S.
Organic Letters, 2013 , vol. 15, # 9 p. 2302 - 2305
反应条件
sodium ethanolate in ethanol Yield given;
参考文献
Michael, Joseph P; De Koning, Charles B; Hosken, Gladys D; Stanbury, Trevor V
Tetrahedron, 2001 , vol. 57, # 47 p. 9635 - 9648
反应条件
1: pyrrolidin-2-one With potassium tert-butylate in tetrahydrofuran T=20°C; 0.166667 h; 2: tris(2-methylphenyl)bismuth dichloride in tetrahydrofuran 3 h; Heating;
参考文献
Ikegai, Kazuhiro; Mukaiyama, Teruaki
Chemistry Letters, 2005 , vol. 34, # 11 p. 1496 - 1497
反应条件
1: Na2HPO4 / CHCl3 2: NaOEt / ethanol / 20 °C View Scheme
参考文献
Michael, Joseph P.; De Koning, Charles B.; Stanbury, Trevor V.
Tetrahedron Letters, 1996 , vol. 37, # 52 p. 9403 - 9406
反应条件
potassium phosphate; [bis(1,10-phenanthroline)copper][bis(pyrrolidin-2-one)copper] in dimethyl sulfoxide T=80°C; 5 h; Inert atmosphere; Reactivity; TimeConcentrationReagent/catalyst; chemoselective reaction;
参考文献
Tye, Jesse W.; Weng, Zhiqiang; Johns, Adam M.; Incarvito, Christopher D.; Hartwig, John F.
Journal of the American Chemical Society, 2008 , vol. 130, # 30 p. 9971 - 9983
反应条件
1,10-phenanthroline in dimethyl sulfoxide T=80°C; 0.75 h; Reactivity; TimeReagent/catalyst; chemospecific reaction;
参考文献
Tye, Jesse W.; Weng, Zhiqiang; Johns, Adam M.; Incarvito, Christopher D.; Hartwig, John F.
Journal of the American Chemical Society, 2008 , vol. 130, # 30 p. 9971 - 9983
参考文献
Billing, D. G.; Boeyens, J. C. A.; Denner, L.; Plooy, K. E. Du; Long, G. C.; Michael, J. P.
Acta Crystallographica, Section B: Structural Science, 1991 , vol. 47, # 2 p. 284 - 288
反应条件
in dimethyl sulfoxide T=80°C; 0.166667 h; Inert atmosphere; Reactivity; Time; chemoselective reaction;
参考文献
Tye, Jesse W.; Weng, Zhiqiang; Johns, Adam M.; Incarvito, Christopher D.; Hartwig, John F.
Journal of the American Chemical Society, 2008 , vol. 130, # 30 p. 9971 - 9983
反应条件
potassium permanganate; water
T=80 - 90°C;
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,205
Full Text Show Details
Lakshminarayana et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 998
