N-乙酰-L-苯丙氨酸乙酯合成路线 （共 48 条）
反应条件
caesium carbonate in acetonitrile 1.5 h; Heating;
参考文献
Lee, Jong Chan; Oh, Yoon Seok; Cho, Sung Hye; Lee, Jung Il
Organic Preparations and Procedures International, 1996 , vol. 28, # 4 p. 480 - 483
反应条件
subtilisin Carlsberg in carbon dioxide T=38°C; transesterification; P=59280 - 60800 Torr; 2.5 h;
参考文献
Yu, Hui-Ming
Journal of the Chinese Chemical Society, 1999 , vol. 46, # 5 p. 647 - 650
反应条件
[Ni0(1,5-cyclooctadiene)2]; methyl dimethoxy silane; tri-cyclo-hexyl-phosphine in toluene T=80°C; 12 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Tobisu, Mamoru; Yamakawa, Ken; Shimasaki, Toshiaki; Chatani, Naoto
Chemical Communications, 2011 , vol. 47, # 10 p. 2946 - 2948
反应条件
(1-methyl-3-(3-sulfopropyl)-1H-imidazol-3-ium)3[PW12O403-] in neat (no solvent) T=100°C; 0.116667 h; Green chemistry; Overall yield = 87 percent;
参考文献
Tetrahedron, , vol. 70, # 13 p. 2237 - 2245
反应条件
hydrogen; [{Rh(μ-Cl)(1,5-cyclooctadiene)}2]; 6-O-(diphenylphosphino)-1,2,3,4-di-O-isopropylidene α-D-glucopyranose in benzene 24 h; Ambient temperature;
参考文献
Yamada, Manubu; Yamashita, Mitsuji; Inokawa, Saburo
Carbohydrate Research, 1981 , vol. 95, p. C9 - C12
反应条件
hydrogen; lt;Rh(bichep)(nbd)gt;ClO4 in tetrahydrofuran T=25°C; P=760 Torr; 0.166667 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 32, # 36 p. 4745 - 4748
反应条件
hydrogen; lt;Rh(COD)(2S,4R)-2-(t-butylaminocarbonyl)-4-lt;3-(t-butylaminocarbonyl)propanoyloxygt;pyrrolidinegt;-lt;ClO4gt; in ethanol T=64.9°C; P=3800 Torr; Title compound not separated from byproducts;
参考文献
Journal of Organometallic Chemistry, , vol. 544, # 2 p. 147 - 156
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (Rc,Ra)-THNAPhos; hydrogen in dichloromethane T=20°C; P=7600.51 Torr; 24 h; AutoclaveInert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 350, # 9 p. 1413 - 1418
反应条件
tert.-butylnitrite; 3 A molecular sieve in dichloromethane T=60°C; 12 h;
参考文献
Suzuki, Masumi; Sugai, Takeshi
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 6 p. 1217 - 1228
反应条件
1: ethanol; D-(+)-Phenylalanine With sulfuric acid; (R)-1-phenyl-ethyl-amine T=80°C; 28 h; 2: acetyl chloride With triethylamine T=20°C; 0.166667 h;
参考文献
Tetrahedron, , vol. 68, # 21 p. 4013 - 4017
