1-(4-氨基苯基)-2,2,2-三氟代乙烷-1-酮合成路线 （共 7 条）
反应条件
ammonia in dimethyl sulfoxide
参考文献
Mertz, Eric; Zimmerman, Steven C.
Journal of the American Chemical Society, 2003 , vol. 125, # 12 p. 3424 - 3425
反应条件
iron; acetic acid in ethanol Heating;
参考文献
Wallace, David M.; Haramura, Masayuki; Cheng, Jie-Fei; Arrhenius, Thomas; Nadzan, Alex M.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 4 p. 1127 - 1130
反应条件
1: 55 percent / Mg / tetrahydrofuran 2: 54 percent / NH3 / dimethylsulfoxide View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 12 p. 3424 - 3425
反应条件
1.1: TBAF / CH2Cl2 / -78 - 20 °C 1.2: 92 percent / aq. HCl / acetone 2.1: 79 percent / Fe; AcOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 4 p. 1127 - 1130
反应条件
manganese(IV) oxide in chloroform 91 h; Ambient temperature;
参考文献
Canadian Journal of Chemistry, , vol. 58, p. 2491 - 2496
参考文献
Kray,W.D.; Rosser,R.W.
Journal of Organic Chemistry, 1977 , vol. 42, # 7 p. 1186 - 1189
反应条件
2: (i) aq. HCl, NaNO2, (ii) /BRN= 3587243/, CuCl
View Scheme
参考文献
Kray,W.D.; Rosser,R.W.
Journal of Organic Chemistry, 1977 , vol. 42, # 7 p. 1186 - 1189
