4-苯基-2(1h)-喹唑啉酮合成路线 （共 12 条）
参考文献
Caprathe, Bradley William; Glase, Shelly Ann; Konstantinou, Zissis; Schelkun, Robert Michael; Sheehan, Susan M.; Thomas, Anthony Jerome; Yuen, Po-Wai
Patent: US2005/96327 A1, 2005 ;
Location in patent: Page/Page column 18 ;
US 20050096327 A1
反应条件
chlorosulphonyl isocyanate in benzene
参考文献
Kamal, Ahmed; Rao, K. Rama; Sattur, P. B.
Synthetic Communications, 1980 , vol. 10, # 10 p. 799 - 804
反应条件
1: tetrahydrofuran / Heating 2: 1) tert-butyllithium / 1) pentane, THF, -20 deg C, 2.5h, 2) 2h, -20 deg C, 3) 1h, room temp. View Scheme
参考文献
Muchowski, Joseph M.; Venuti, Michael C.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4798 - 4801
反应条件
tert.-butyl lithium 1) pentane, THF, -20 deg C, 2.5h, 2) 2h, -20 deg C, 3) 1h, room temp.; Yield given. Multistep reaction;
参考文献
Muchowski, Joseph M.; Venuti, Michael C.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4798 - 4801
反应条件
2: 1a.) n-BuLi, 1b.) Li, naphthalene / 1a.) THF, hexane, 0 deg C, 10 min, 1b.) -40 deg C, 2.) to 20 deg C, 1 h View Scheme
参考文献
Guijarro, Albert; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1993 , vol. 49, # 2 p. 469 - 482
反应条件
n-butyllithium; naphthalene; lithium 1a.) THF, hexane, 0 deg C, 10 min, 1b.) -40 deg C, 2.) to 20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Guijarro, Albert; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1993 , vol. 49, # 2 p. 469 - 482
反应条件
in benzene 1.) 0 deg C to 5 deg C, 60 min, 2.) 28 deg C, 3 h;
参考文献
Kamal, Ahmed; Rao, K. Rama; Sattur, P. B.
Synthetic Communications, 1980 , vol. 10, # 10 p. 799 - 804
反应条件
1: tin dichloride; fuming hydrochloric acid 2: 195 °C View Scheme
参考文献
Gabriel; Stelzner
Chemische Berichte, 1896 , vol. 29, p. 1313
反应条件
Yield given. Multistep reaction;
参考文献
Bergman, Jan; Brynolf, Anna; Elman, Bjoern; Vuorinen, Eino
Tetrahedron, 1986 , vol. 42, # 13 p. 3697 - 3706
反应条件
phosphorodiimidate in diphenylether T=250°C; 3 h;
参考文献
Kamal, Ahmed; Rao, Maddamsetty Venkateswara; Sattur, Pralhad Balvantrao
Heterocycles, 1986 , vol. 24, # 11 p. 3075 - 3078
