5-甲氧基-2-硝基苯甲酸甲酯合成路线 （共 12 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 49 ;
反应条件
hydrogenchloride in water T=0 - 20°C; 22 h; Heating / reflux;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2005/121152 A1, 2005 ;
Location in patent: Page/Page column 30 ;
WO 2005/121152 A1
反应条件
1: 3-carboxy-4-nitrophenol With potassium carbonate in DMF (N,N-dimethyl-formamide) 0.25 h; 2: methyl iodide in DMF (N,N-dimethyl-formamide) T=75°C; 4 h;
参考文献
WO2003/97641 A2, ;
Page/Page column 63-64 ;
WO 03/097641 A2
反应条件
in methanol; dichloromethane T=20°C; 10 h;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 8 p. 2587 - 2602
反应条件
copper quinolate in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
thionyl chloride; sodium in methanol
参考文献
US5457105 A1, ;
US 5457105 A
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 16, p. 1097 - 1101
Zhurnal Organicheskoi Khimii, , vol. 16, # 6 p. 1268 - 1274
参考文献
Journal of the Chemical Society, , p. 2702,2703
反应条件
in acetonitrile T=30°C; KineticsThermodynamic data;
参考文献
Journal of the Chemical Society, Perkin Transactions 2, , # 8 p. 1449 - 1454
反应条件
hydrogen; triethylamine; palladium hydroxide on carbon in N,N-dimethyl-formamide T=20°C;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 50 ;
