3-乙氧基-3-亚氨基丙酸乙酯盐酸盐合成路线 （共 25 条）
参考文献
Pinner
Chemische Berichte, 1895 , vol. 28, p. 476
反应条件
anhydrous sodium hydrogen carbonate; sodium nitrite in water; acetic acid
参考文献
Takeda Chemical Industries, Ltd.
Patent: US3941823 A1, 1976 ;
反应条件
1: K2CO3 / diethyl ether; H2O 2: 76 percent / NH4Cl / ethanol / 8 h / Heating View Scheme
参考文献
Kobayashi; Inoue; Kita; Yoshiya; Nishino; Oizumi; Kimura
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 5 p. 788 - 796
反应条件
in methanol T=0°C; 1.91667 h; RefluxInert atmosphere;
参考文献
Ginzinger, Werner; Muehlgassner, Gerhard; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Reithofer, Michael; Berger, Walter; Keppler, Bernhard K.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3398 - 3413
反应条件
1: NH4Cl; K2CO3 / ethanol / 24 h / 22 °C 2: K2CO3 / ethanol / Heating View Scheme
参考文献
Pittala, Valeria; Romeo, Giuseppe; Salerno, Loredana; Siracusa, Maria Angela; Modica, Maria; Materia, Luisa; Mereghetti, Ilario; Cagnotto, Alfredo; Mennini, Tiziana; Marucci, Gabriella; Angeli, Piero; Russo, Filippo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 1 p. 150 - 153
反应条件
potassium carbonate in diethyl ether; water Yield given;
参考文献
CURIS, INC.
Patent: WO2008/33747 A2, 2008 ;
Location in patent: Page/Page column 254-255 ;
反应条件
1: NH4Cl; K2CO3 / ethanol / 24 h / 22 °C 2: K2CO3 / ethanol / Heating View Scheme
参考文献
Pittala, Valeria; Romeo, Giuseppe; Salerno, Loredana; Siracusa, Maria Angela; Modica, Maria; Materia, Luisa; Mereghetti, Ilario; Cagnotto, Alfredo; Mennini, Tiziana; Marucci, Gabriella; Angeli, Piero; Russo, Filippo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 1 p. 150 - 153
参考文献
Pinner
Chemische Berichte, 1895 , vol. 28, p. 476
反应条件
P=29420.3 Torr; Hydrogenation;
参考文献
Ges.Kohlentechnik.
Patent: DE604277 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 208
反应条件
triethylamine in ethanol
T=80°C; 2 h;
参考文献
Chiba; Takahashi; Sakaki; Kaneko
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 3046 - 3049
