4-(2,2-二甲基丙基)-苯酚合成路线 (共 6 条)
反应条件
1: tetrahydrofuran; pentane / 1 h / 0 °C / Inert atmosphere 2: hydrogenchloride; palladium 10 on activated carbon; hydrogen / ethanol; water / 14 h View Scheme
参考文献
Tello-Aburto, Rodolfo; Kalstabakken, Kyle A.; Volp, Kelly A.; Harned, Andrew M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 22 p. 7849 - 7859
反应条件
n-butyllithium; potassium tert-butylate; 2-methyl-2-iodopropane 1.) heptane, hexane, reflux, 20 h, 2.) THF; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bates, Robert B.; Siahaan, Teruna J.
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1432 - 1434
反应条件
n-butyllithium; potassium tert-butylate 1.) heptane, hexane, reflux, 20 h, 2.) THF; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bates, Robert B.; Siahaan, Teruna J.
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1432 - 1434
反应条件
1: With 3-chloro-benzenecarboperoxoic acid 2: hydrolysis;
参考文献
Koyama, Hiroo; Boueres, Julia K.; Miller, Daniel J.; Berger, Joel P.; MacNaul, Karen L.; Wang, Pei-Ran; Ippolito, Marc C.; Wright, Samuel D.; Agrawal, Arun K.; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3347 - 3351
参考文献
Bygden
Journal fuer Praktische Chemie (Leipzig), 1920 , vol. <2>100, p. 16
反应条件
N,N-diisopropylmethyl amine; sulfuryl dichloride
参考文献
Koyama, Hiroo; Boueres, Julia K.; Miller, Daniel J.; Berger, Joel P.; MacNaul, Karen L.; Wang, Pei-Ran; Ippolito, Marc C.; Wright, Samuel D.; Agrawal, Arun K.; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3347 - 3351