5-甲氧基苯并呋喃-2-甲醛合成路线 （共 11 条）
反应条件
manganese(IV) oxide in ethyl acetate T=20°C; 26 h;
参考文献
SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2005/68460 A1, 2005 ;
Location in patent: Page/Page column 313 ;
WO 2005/068460 A1
反应条件
acetic acid 16 h; Reflux;
参考文献
UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE; EVERETT, Steven, Albert; ULHAQ, Saraj
Patent: WO2010/125350 A1, 2010 ;
Location in patent: Page/Page column 45 ;
WO 2010/125350 A1
反应条件
1: 71 percent / diisobutylaluminum hydride / tetrahydrofuran / 4 h / Ambient temperature 2: 60 percent / MnO2 / ethyl acetate / 3 h / Ambient temperature View Scheme
参考文献
Lau, Cheuk K.; Belanger, Patrice C.; Dufresne, Claude; Scheigetz, John; Therien, Michael; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1299 - 1318
反应条件
1: potassium carbonate / dimethylformamide 2: acetic acide / Heating View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
acetic acid Heating;
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
参考文献
Mukhanova; Kukushkin; Ivanov; Alekseeva; Granik
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 325 - 329
反应条件
sodium tetrahydroborate in ethanol; chloroform
T=30 - 40°C; 1 h;
参考文献
Mukhanova; Kukushkin; Ivanov; Alekseeva; Granik
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 325 - 329
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
1: 87 percent
2: trimethylbenzyl ammonium hydroxide
3: hydrogen / Raney nickel / ethanol
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
1: 87 percent
2: trimethylbenzyl ammonium hydroxide
3: hydrogen / Raney nickel / ethanol
4: 72 percent
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
