formic acid; [{(η6-C6Me6)Ru(μ-Cl)Cl}2]; (S)-2-PipSNH2Cl; triethylamine T=30°C; 24 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

1: With (S)-N-(3-methyl-1-(1-pyrrolidin-1-yl)butan-2-yl) diphenylphosphinic amideamine in hexane T=20°C; 6 h; Inert atmosphere; 2: With ammonium chloride in hexane; water T=0°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 6 h;

(1R,2R)-α,α,α',α'-tetraphenyl-1,2-cyclohexanedimethanol; TiF4 in CH3CN 1) THF, hexane, 0 deg C to RT, 20 min, 2) THF, hexane, 20 min, 3) THF, hexane, -10 deg C, 12 h then warm to RT; Yield givenMultistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

dimethylsulfide borane complex; (R)-tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole in tetrahydrofuran T=0°C; 0.666667 h;

sol-gel silica (prepared using tetraethoxysilane, phenyltriethoxysilane, diethylmethylsilane) supported Pseudomonas fluorescens lipase AK; sol-gel silica (prepared using tetraethoxysilane, phenyltriethoxysilane, diethylmethylsilane) supported Novozym CaLB L: Candida antartica recombinant lipase B expressed in Aspergillus niger in hexane; tert-butyl methyl ether T=60°C; 24 h; Enzymatic reaction;

1: methylmagnesium bromide With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol in toluene T=-40°C; 0.166667 h; Inert atmosphere; 2: thiophene-2-carbaldehyde in toluene T=-40°C; Grignard reaction; 4 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

1: With (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol; titanium (IV) isopropoxide in toluene T=-40°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in water Inert atmosphere; optical yield given as percent eeenantioselective reaction;

Birman's catalyst; N-ethyl-N,N-diisopropylamine; (Piv)2O in diethyl ether T=20°C; 12 h; optical yield given as percent eeenantioselective reaction;

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