6-甲氧基吲哚-3-乙腈合成路线 （共 18 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; dichloromethane; ethyl acetate; toluene
参考文献
Centre National de la Recherche Scientifique
Patent: EP2266562 A1, 2010 ;
反应条件
in dimethyl sulfoxide; ethyl acetate T=80°C;
参考文献
Faul, Margaret M.; Engler, Thomas A.; Sullivan, Kevin A.; Grutsch, John L.; Clayton, Marcella T.; Martinelli, Michael J.; Pawlak, Joseph M.; LeTourneau, Michael; Coffey, D. Scott; Pedersen, Steven W.; Kolis, Stanley P.; Furness, Kelly; Malhotra, Sushant; Al-Awar, Rima S.; Ray, James E.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 2967 - 2975
反应条件
methyl-magnesium iodide; diethyl ether Behandeln des Reaktionsgemisches mit Chloracetonitril;
参考文献
Chemische Berichte, , vol. 63, p. 2245,2247
反应条件
in ethanol 24 h; Heating;
参考文献
Drost; Jones; Cava
Journal of Organic Chemistry, 1989 , vol. 54, # 25 p. 5985 - 5988
反应条件
tetrahydrofuran; acetic acid; dimethyl sulfate Erwaermen des Reaktionsprodukts in H2O mit KCN;
参考文献
Journal of the American Chemical Society, , vol. 81, p. 2481,2490
反应条件
1: Zn, NH4Cl / ethanol; H2O 2: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 3: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 4: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 5: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 6: ethanol / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 2: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 3: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 4: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 5: ethanol / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h 2: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 3: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 4: ethanol / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 3: ethanol / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 2: ethanol / 2 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
