2,4-二甲基噁唑-5-羧酸乙酯合成路线 （共 10 条）
反应条件
acetic acid 22 h; Heating;
参考文献
Boulos, John; Stujenske, Christina
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 2 p. 443 - 445
反应条件
1: ethyl acetoacetate With PhI(ODNs)OH 0.0111111 h; microwave irradiation; 2: acetamide 0.0333333 h; microwave irradiation;
参考文献
Lee, Jong Chan; Choi, Hyun Jung; Lee, Yong Chan
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 123 - 125
反应条件
potassium acetate; (NH4)2CO3; acetic anhydride T=110°C; 2 h;
参考文献
Kondrat'ewa,G.Y.; Tschshi-Chen,K.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 2348 - 2353,2315 - 2320
反应条件
1: SO2Cl2 2: 26 percent / HCOOH View Scheme
参考文献
Boulos, John; Schulman, Jerome
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 4 p. 859 - 863
反应条件
ammonium acetate; acetic acid
参考文献
Cornforth; Cornforth
Journal of the Chemical Society, 1953 , p. 93,95
参考文献
Cornforth; Cornforth
Journal of the Chemical Society, 1953 , p. 93,95
反应条件
1: 80 percent / LiAlH4 / diethyl ether / 2.5 h / -100 °C 2: 49 percent / oxalyl chloride, DMSO / CH2Cl2 / 0.25 h / -5 °C View Scheme
参考文献
Boulos, John; Schulman, Jerome
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 4 p. 859 - 863
反应条件
lithium aluminium tetrahydride in diethyl ether T=-100°C; 2.5 h;
参考文献
Aguado, Andreina; Boulos, John; Carreras, Anladys; Montoya, Angelica; Rodriquez, Judith
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 6 p. 1517 - 1520
反应条件
1: With methanol; lithium hydroxide; water in tetrahydrofuran T=0 - 20°C; 2: With hydrogenchloride in tetrahydrofuran; water T=0 - 20°C; pH=3;
参考文献
Wyeth
Patent: US2006/19965 A1, 2006 ;
Location in patent: Page/Page column 22-23 ;
US 20060019965 A1
反应条件
1: 80 percent / lithium aluminum hydride / diethyl ether / -10 °C
2: 54.6 percent / triphenyl phosphine / CCl4 / 2 h / Heating
View Scheme
参考文献
Boulos, John; Stujenske, Christina
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 2 p. 443 - 445
