反应条件
1: 2,4,5-tribromo-1H-imidazole With sodium hydride in tetrahydrofuran; mineral oil
T=0°C; Inert atmosphere;
2: bromomethyl-methyl-ether in tetrahydrofuran; mineral oil
T=0 - 20°C; Inert atmosphere;
参考文献
Niculescu-Duvaz, Dan; Niculescu-Duvaz, Ion; Suijkerbuijk, Bart M.J.M.; Menard, Delphine; Zambon, Alfonso; Nourry, Arnaud; Davies, Lawrence; Manne, Helen A.; Friedlos, Frank; Ogilvie, Lesley; Hedley, Douglas; Takle, Andrew K.; Wilson, David M.; Pons, Jean-Francois; Coulter, Tom; Kirk, Ruth; Cantarino, Neus; Whittaker, Steven; Marais, Richard; Springer, Caroline J.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6934 - 6952