2-溴-4-氯吡啶合成路线

百科

结构式

环氧丙烷冰醋酸 63148-62-9 MDI 丁酮二甲基亚砜碳酸氢钠 471-34-1

2-溴-4-氯吡啶合成路线（共 6 条）

19798-80-22-氨基-4-氯吡啶→22918-01-02-溴-4-氯吡啶

参考文献

SMITHKLINE BEECHAM CORPORATION; VITAE PHARMACEUTICALS, INC.
Patent: WO2008/124582 A1, 2008 ;
Location in patent: Page/Page column 92-93 ;
WO 2008/124582 A1

626-61-94-氯吡啶→22918-01-02-溴-4-氯吡啶

参考文献

Choppin, Sabine; Gros, Philippe; Fort, Yves
European Journal of Organic Chemistry, 2001 , # 3 p. 603 - 606

124-41-4甲醇钠+22918-01-02-溴-4-氯吡啶→89488-29-92-溴-4-甲氧基吡啶

参考文献

WO2014/74422 A1, ;

Paragraph 00162 ;

75-77-4三甲基氯硅烷+22918-01-02-溴-4-氯吡啶→139585-50-54-氯-2-三甲基甲硅烷基吡啶

参考文献

Chemische Berichte, , vol. 125, # 5 p. 1131 - 1140

22918-01-02-溴-4-氯吡啶→1010115-57-74-氯-2-乙炔-吡啶

参考文献

JANSSEN PHARMACEUTICA NV; Gijsen, Henricus Jacobus Maria; De Cleyn, Michel Anna Jozef; Surkyn, Michel; Verbist, Bie Maria Pieter
Patent: US2013/324529 A1, 2013 ;

22918-01-02-溴-4-氯吡啶→1762-41-04,4'-二氯-2,2'-联吡啶

参考文献

Garcia-Lago, Ramon; Alonso-Gomez, Jose-Lorenzo; Sicre, Cristina; Cid, Maria-Magdalena
Heterocycles, 2008 , vol. 75, # 1 p. 57 - 64