2-巯基-5-甲基苯并恶唑合成路线 （共 11 条）
反应条件
1: in ethanol Reflux; 2: With acetic acid in water pH=5;
参考文献
GALLEON PHARMACEUTICALS, INC.
Patent: US2011/224269 A1, 2011 ;
Location in patent: Page/Page column 21 ;
反应条件
acetic acid in ethanol; water
参考文献
InterMune, Inc.
Patent: US2009/269305 A1, 2009 ;
反应条件
potassium hydroxide in methanol; water
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 7 p. 913 - 923
反应条件
1: H2 / Pd-C / ethanol 2: KOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 15, # 10 p. 3515 - 3523
反应条件
2-amino-4-methyl-phenol in benzene 1 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 6 p. 1518 - 1524
反应条件
in acetic acid 1 h; Heating;
参考文献
Ocura, Haruo; Mineo, Satoshi; Nakagawa, Kunio
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 6 p. 1518 - 1524
反应条件
in benzene 9 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 6 p. 1518 - 1524
反应条件
1: 93 percent / ethanol / 1 h / Ambient temperature 2: 73 percent / benzene / 9 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 6 p. 1518 - 1524
反应条件
in benzene 1 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 6 p. 1518 - 1524
反应条件
potassium carbonate in acetone
T=20°C; 20 h;
参考文献
AMR TECHNOLOGY, INC.
Patent: US2009/82359 A1, 2009 ;
Location in patent: Page/Page column 62-63 ;
US 20090082359 A1
