5-甲基-1,3-苯并噁唑-2(3H)-酮合成路线 （共 20 条）
反应条件
in acetonitrile T=23 - 70°C;
参考文献
VICURON PHARMACEUTICALS INC.
Patent: US2006/211603 A1, 2006 ;
Location in patent: Page/Page column 68 ;
反应条件
triethylamine in dichloromethane T=0 - 20°C; Inert atmosphere;
参考文献
YALE UNIVERSITY; JORGENSEN, William; BUCALA, Richard, J.
Patent: WO2010/21693 A2, 2010 ;
Location in patent: Page/Page column 33 ;
参考文献
BEECHAM GROUP PLC
Patent: EP200345 A3, 1988 ;
反应条件
hydrogenchloride; potassium carbonate; triethylamine in chloroform; water
参考文献
MITSUBISHI TANABE PHARMA CORPORATION
Patent: US2012/196824 A1, 2012 ;
反应条件
selenium; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine in toluene T=150°C; P=22800 Torr; 7 h;
参考文献
Wang, Xiaofang; Ling, Gang; Xue, Yan; Lu, Shiwei
European Journal of Organic Chemistry, 2005 , # 8 p. 1675 - 1679
反应条件
in N,N-dimethyl-formamide T=145 - 150°C; 3.5 h;
参考文献
Aida R. Nadji-Boukrouche; Khoumeri, Omar; Terme, Thierry; Liacha, Messaoud; Vanellec, Patrice
Arkivoc, 2010 , vol. 2010, # 10 p. 358 - 370
反应条件
copper dichloride; sodium t-butanolate in N,N-dimethyl-formamide T=25°C; 5 h;
参考文献
Liu, Qiang; Wu, Pan; Yang, Yuhong; Zeng, Ziqi; Liu, Jie; Yi, Hong; Lei, Aiwen
Angewandte Chemie - International Edition, 2012 , vol. 51, # 19 p. 4666 - 4670
反应条件
sodium azide; iodine; sodium hydrogencarbonate in N,N-dimethyl-formamide T=100°C; 2 h;
参考文献
Rajendar; Kant, Ruchir; Narender
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3591 - 3596
反应条件
carbon monoxide; triethylamine in 1,2-dichloro-benzene T=200°C; P=60800 Torr; 8 h; Further byproducts given;
参考文献
Gazzetta Chimica Italiana, , vol. 123, # 12 p. 683 - 686
反应条件
in 1,4-dioxane T=20°C; 4 h;
参考文献
Singh; Singh, Pallavi; Singh, Shweta
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2007 , vol. 46, # 10 p. 1666 - 1671
