(S)-(+)-2-氨基-3-羟基-3-甲基丁酸合成路线 （共 11 条）
反应条件
1: With sodium hydride in tetrahydrofuran T=20°C; 0.116667 h; 2: With hydrogenchloride in methanol Heating;
参考文献
Belokon, Yuri N.; Kochetkov, Konstantin A.; Ikonnikov, Nikolai S.; Strelkova, Tatiana V.; Harutyunyan, Syuzanna R.; Saghiyan, Ashot S.
Tetrahedron Asymmetry, 2001 , vol. 12, # 3 p. 481 - 485
反应条件
nickel nitrate; water; triethyl amine hydrochloride; triethylamine 1.) MeOH, 2 h, 50 deg C; 2.) MeOH, 50 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 107, # 14 p. 4252 - 4259
反应条件
nickel nitrate; water; triethyl amine hydrochloride; triethylamine 1.) MeOH, 2 h, 50 deg C; 2.) MeOH, 50 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 107, # 14 p. 4252 - 4259
反应条件
1: O2, OH- / H2O 2: H2O / Irradiation View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 47, p. 1029 - 1036
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Nature Chemistry, , vol. 2, # 4 p. 280 - 285
反应条件
in water Irradiation;
参考文献
Canadian Journal of Chemistry, , vol. 47, p. 1029 - 1036
反应条件
hydrogen iodide T=153°C; 5 h; sealed tube; Product distribution;
参考文献
Aoyagi, Yasuo; Sugahara, Tatsuyuki
Phytochemistry (Elsevier), 1988 , vol. 27, # 10 p. 3306 - 3307
反应条件
triethylamine in DMF (N,N-dimethyl-formamide) T=20°C; 18 h;
参考文献
WO2004/54974 A2, ;
Page 199 ;
WO 2004/054974 A2
反应条件
sodium hydrogencarbonate
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 16 p. 4329 - 4332
