反式-3-苯基环氧丙酸乙酯合成路线 （共 11 条）
参考文献
Pfau; Plattner
Helvetica Chimica Acta, 1932 , vol. 15, p. 1250,1265
反应条件
1: 1.) hydrogen bromide, 2.) sodium carbonate / 1.) toluene, 8 h, 2.) water, acetone, 50 deg C, 3.5 h 2: 1.) sodium ethoxide, 2.) water / 1.) ethanol, 5 min View Scheme
参考文献
Thijs, Lambertus; Orskamp Jos; Adriaan; Marielle; Eenstra, Rolf W.; Legters, Johan; Zwanenburg, Binne
Tetrahedron, 1990 , vol. 46, # 7 p. 2611 - 2622
反应条件
sodium tetrahydroborate; iron(II) chloride in ethanol T=30°C; 20 h;
参考文献
Yanada; Meguri
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 12 p. 3423 - 3425
反应条件
triphenylphosphine in ethanol T=65°C; 120 h; other reaction conditions, other α,β-epoxy esters; Product distributionMechanism;
参考文献
Vedejs, Edwin; Fleck, Thomas J.
Journal of the American Chemical Society, 1989 , vol. 111, # 15 p. 5861 - 5871
反应条件
1: H2S, aq. NaOH / methanol
2: SOCl2 / benzene
3: aq. NaOH / methanol
View Scheme
参考文献
Tung,C.C.; Speziale,A.J.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1577 - 1579
反应条件
niobium pentachloride; zinc in tetrahydrofuran; benzene
T=23°C; 24 h; Inert atmosphere;
参考文献
Oh, Kyungsoo; Knabe, William Eric
Tetrahedron, 2009 , vol. 65, # 15 p. 2966 - 2974
反应条件
triphenylphosphine in ethanol
T=65°C; 120 h; other reaction conditions, other α,β-epoxy esters; Product distributionMechanism;
参考文献
Vedejs, Edwin; Fleck, Thomas J.
Journal of the American Chemical Society, 1989 , vol. 111, # 15 p. 5861 - 5871
参考文献
Culvenor et al.
Journal of the Chemical Society, 1949 , p. 278,280, 2573, 2576
参考文献
Pfau; Plattner
Helvetica Chimica Acta, 1932 , vol. 15, p. 1250,1265
反应条件
trifluoroacetic anhydride in dichloromethane
T=20°C; 3 h; regioselective reaction;
参考文献
Roscales, Silvia; Csaky, Aurelio G.
Chemical Communications, 2014 , vol. 50, # 4 p. 454 - 456
