3-甲基-2(5H)-呋喃酮合成路线 （共 48 条）
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 2729 - 2734
反应条件
2-(dimethylamino)-ethanol; formic acid; dihydrogen peroxide in dichloromethane T=20°C; 12 h;
参考文献
Von der Ohe; Bruckner
New Journal of Chemistry, 2000 , vol. 24, # 9 p. 659 - 669
反应条件
thionyl chloride
1 h; Heating; Yield given;
参考文献
Johnson, Alan W.; Gowda, Gopala; Hassanali, Ahmed; Knox, John; Monaco, Sam; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1734 - 1743
反应条件
1: SOCl2 / 1 h / Heating
2: 1,2-dimethoxy-ethane / 16 h / 5 °C
View Scheme
参考文献
Johnson, Alan W.; Gowda, Gopala; Hassanali, Ahmed; Knox, John; Monaco, Sam; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1734 - 1743
反应条件
triethylamine in dichloromethane
T=0 - 20°C;
参考文献
Zheng, Xiao; Dai, Xi-Jie; Yuan, Hong-Qiu; Ye, Chen-Xi; Ma, Jie; Huang, Pei-Qiang
Angewandte Chemie - International Edition, 2013 , vol. 52, # 12 p. 3494 - 3498
Angew. Chem., 2013 , vol. 125, # 12 p. 3578 - 3582,5
反应条件
lithium diisopropyl amide
T=-78 - 0°C; 1.16667 h;
参考文献
Von der Ohe; Bruckner
New Journal of Chemistry, 2000 , vol. 24, # 9 p. 659 - 669
反应条件
1.1: 99 percent / Et3N / CH2Cl2 / 1.5 h / 20 °C
2.1: silver(I) trifluoroacetate / CH2Cl2 / -78 °C
2.2: 58 percent / CH2Cl2 / 1 h / -78 - 20 °C
View Scheme
参考文献
Rosso, Giovanni B.; Pilli, Ronaldo A.
Tetrahedron Letters, 2006 , vol. 47, # 2 p. 185 - 188
反应条件
copper(l) iodide; cyclohexenon; tert.-butyl lithium
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Cruz-Almanza, Raymundo; Higareda, Fernando Padilla
Heterocycles, 1992 , vol. 34, # 12 p. 2323 - 2330
